Selected Publications

1. TLR7 activation by miR-21 promotes renal fibrosis by activating the pro-inflammatory signaling pathway in tubule epithelial cells. Kim J, Ha S, Son M, Kim D, Kim MJ, Kim B, Kim D, Chung HY, Chung KW. Cell Commun Signal. 2023 Aug 18;21(1):215.

2. Diminished Tubule Epithelial Farnesoid X Receptor Expression Exacerbates Inflammation and Fibrosis Response in Aged Rat Kidney. Ha S, Yang Y, Won Kim J, Son M, Kim D, Kim MJ, Im DS, Young Chung H, Chung KW. J Gerontol A Biol Sci Med Sci. 2023 Jan 26;78(1):60-68.

3. Activation of PAR2 promotes high-fat diet-induced renal injury by inducing oxidative stress and inflammation. Ha S, Yang Y, Kim BM, Kim J, Son M, Kim D, Yu HS, Im DS, Chung HY, Chung KW. Biochim Biophys Acta Mol Basis Dis. 2022 Oct 1;1868(10):166474.

4. Targeting fatty acid metabolism for fibrotic disorders. Hwang S, Chung KW. Arch Pharm Res. 2021 Oct;44(9-10):839-856.

5.Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis. Chung KW, Dhillon P, Huang S, Sheng X, Shrestha R, Qiu C, Kaufman BA, Park J, Pei L, Baur J, Palmer M, Susztak K. Cell Metab. 2019 Oct 1;30(4):784-799.

6.DNMT1 in Six2 Progenitor Cells Is Essential for Transposable Element Silencing and Kidney Development. Li SY, Park J, Guan Y, Chung KW, Shrestha R, Palmer MB, Susztak K. J Am Soc Nephrol. 2019 Apr;30(4):594-609.

7. Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming. Huang S, Park J, Qiu C, Chung KW, Li SY, Sirin Y, Han SH, Taylor V, Zimber-Strobl U, Susztak K. PLoS Biol. 2018 Sep 18;16(9):e2005233.

8. Impairment of PPARα and the Fatty Acid Oxidation Pathway Aggravates Renal Fibrosis during Aging. Chung KW, Lee EK, Lee MK, Oh GT, Yu BP, Chung HY. J Am Soc Nephrol. 2018 Apr;29(4):1223-1237.

9. The critical role played by endotoxin-induced liver autophagy in the maintenance of lipid metabolism during sepsis. Chung KW, Kim KM, Choi YJ, An HJ, Lee B, Kim DH, Lee EK, Im E, Lee J, Im DS, Yu BP, Chung HY. Autophagy. 2017 Jul 3;13(7):1113-1129.

10. Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome/IL-1β for steatohepatitis. Chung KW, Lee EK, Kim DH, An HJ, Kim ND, Im DS, Lee J, Yu BP, Chung HY. Aging Cell. 2015 Aug;14(4):524-33.