학력 Education

2007.02       Ph.D. in Toxicology (Seoul National University College of Pharmacy, Korea)
                     Thesis advisor: Prof. Young-Chul Kim, Ph.D.

 경력 Experience

2007. 03 - 2007. 11      Postdoctoral Fellow (Seoul National University College of Pharmacy, Korea)

2007. 11 - 2008. 06      Research Scholar (Wayne State University School of Medicine, Karmanos Cancer Institute, USA)

2008. 07 - 2010. 07      Postdoctoral Fellow (Wayne State University School of Medicine, Karmanos Cancer Institute, USA)

2010. 07 - 2013. 04      Research Associate (Wayne State University School of Medicine, Karmanos Cancer Institute, USA)

2013. 05 - 2013. 08      Research Assistant Professor (Chungbuk National University College of Pharmacy, Korea)

2013. 09 - 2017. 08      Assistant Professor (Pusan National University College of Pharmacy)

2017. 09 - 2022. 08      Associate Professor (Pusan National University College of Pharmacy)

2022. 09  - present        Professor (Pusan National University College of Pharmacy)

 연구업적 Achievements

1. Kim JE, Yun WB, Sung JE, Lee HA, Choi JY, Choi YS, Jung YS, Kim KS, Hwang DY. Characterization the response of Korl:ICR mice to loperamide induced constipation. Lab Anim Res.32(4):231-240, 2016

2. Jung YS,Kim SN, Kwon HJ, Seong JK, Granneman JG, Lee YH. Sex differences in sympathetic innervation and browning of white adipose tissue of mice. Biology of Sex Differences7(67):1-13, 2016

3. Koh EK, Kim JE, Go J, Song SH, Sung JE, Son HJ, Jung YJ, Kim BH, Jung YS, Hwang DY. Protective effects of the antioxidant extract collected from Styela clava tunics on UV radiation?induced skin aging in hairless mice. Int J Mol Med.38(5):1565-1577, 2016

4. Lee YH, Kim SH, Kim SN, Kwon HJ, Kim JD, Oh JY, Jung YS*. Sex-specific metabolic interactions between liver and adipose tissue in MCD diet-induced non-alcoholic fatty liver disease. Oncotarget7(30):46959-46971, 2016

5. Lee YH, Kim JH, Kim SH, Oh JY, Seo WD, Kim KM, Jung JC, Jung YS*. Barley Sprouts Extract Attenuates Alcoholic Fatty Liver Injury in Mice by Reducing Inflammatory Response. Nutrients8(7):1-13, 2016

6. Lee YH, Yun JS, Jung JC, Oh S, Jung YS*. Anti-tumor activity of benzylidene-acetophenone derivatives via proteasomal inhibition in prostate cancer cells. Pharmazie71(5):274-279, 2016

7. Kim SH, Oh DS, Oh JY, Son TG, Yuk DY, Jung YS*. Silymarin prevents restraint stress-induced acute liver injury by ameliorating oxidative stress and reducing inflammatory response. Molecules21(4):443; 1-10, 2016

8. Song SH, Kim JE, Go J, Koh EK, Sung JE, Lee HA, Choi KM, Kim HD, JungYS, Kim KS, Hwang DY. Comparison of the response using ICR mice derived from three different sources to ethanol/hydrochloric acid-induced gastric injury. Lab Anim Res.32(1):56-64, 2016

9. Jung JC, Lee YH, Kim SH, Kim KJ, Kim KM, Oh S, Jung YS*. Hepatoprotective effect of licorice, the root of Glycyrrhiza uralensis Fischer, in alcohol-induced fatty liver disease.BMC Complement Altern Med. 16(1):19-29, 2016

10. Kim SM, Kim BY, Son Y, Jung YS, Eo SK, Park YC, Kim K. 7α-Hydroxycholesterol induces inflammation by enhancing production of chemokine (C-C motif) ligand 2. Biochem Biophys Res Commun.467(4):879-884, 2015

11. Lee Y, Chun HJ, Lee KM, Jung YS, Lee J. Silibinin suppresses astroglial activation in a mouse model of acute Parkinson?s disease by modulating the ERK and JNK signaling pathways. Brain Res.1627:233-242, 2015

12. Kim DH, Lee DH, Jo MR, Son DJ, Park MH, Hwang CJ, Park JH, Yuk DY, Yoon do Y, Jung YS, Kim Y, Jeong JH, Han SB, Hong JT. Exacerbation of collagen antibody-induced arthritis in transgenic mice overexpressing peroxiredoxin 6. Arthritis Rheumatol 67(11):3058-3069, 2015

13. Han JY, Cho SS, Yang JH, Kim KM, Jang CH, Park da E, Bang JS, Jung YS, Ki SH. The chalcone compound isosalipurposide (ISPP) exerts a cytoprotective effect against oxidative injury via Nrf2 activation. Toxicol Appl Pharmacol287(1):77-85,

2015

14. Kim SM, Lee CW, Kim BY, Jung YS, Eo SK, Park YC, Kim K. 27-Oxygenated cholesterol induces expression of CXCL8 in macrophages via NF-κB and CD88. Biochem Biophys Res Commun463(4):1152-1158, 2015

15. Yu JY, Ha JY, Kim KM, Jung YS, Jung JC, Oh S. Anti-Inflammatory Activities of Licorice Extract and Its Active Compounds, Glycyrrhizic Acid, Liquiritin and Liquiritigenin, in BV2 Cells and Mice Liver. Molecules20(7):13041-13054, 2015

16. Kim AY, Kwak JH, Je NK, Lee YH, Jung YS*. Epithelial-mesenchymal Transition is Associated with Acquired Resistance to 5-Fluorouracil in HT-29 Colon Cancer Cells.

Toxicol Res.31(2):151-156, 2015

17. Lee DH, Kim DH, Hwang CJ, Song S, Han SB, Kim Y, Yoo HS, Jung YS, Kim SH, Yoon do Y, Hong JT. Interleukin-32 γ attenuates ethanol-induced liver injury by the inhibition of cytochrome P450 2E1 expression and inflammatory responses. Clin Sci (Lond).128(10):695-706, 2015

18. Han EB, Chang BY, Jung YS, Kim SY. Lantana camara Induces Apoptosis by Bcl-2 Family and Caspases Activation. Pathol Oncol Res21(2):325-331, 2015

19. D'Angelo RC, Liu XW, Najy AJ, Jung YS, Won J, Chai KX, Fridman R, Kim HR. TIMP-1 via TWIST1 Induces EMT Phenotypes in Human Breast Epithelial Cells. Mol Cancer Res.12(9):1324-1333, 2014

20. Jung YS, Kim DH, Hwang JY, Yun NY, Lee YH, Han SB, Hwang BY, Lee MS, Jeong HS, Hong JT. Anti-inflammatory effect of tricin 4'-O-(threo-β-guaiacylglyceryl) ether, a novel flavonolignan compound isolated from Njavara on in RAW264.7 cells and in ear mice edema. Toxicol Appl Pharmacol.277(1):67-76, 2014

21. Choi KE, Jung YS, Kim DH, Song JK, Kim JY, Jung YY, Eum SY, Kim JH, Yoon NY, Yoo HS, Han SB, Hong JT. Myriocin induces apoptotic lung cancer cell death via activation of DR4 pathway. Arch Pharm Res.37(4):501-511, 2014

22. Lee YH, Jung YS, Choi D. Recent advance in brown adipose physiology and its therapeutic potential. Exp Mol Med.46:e78, 2014

23. Ban JO*, Jung YS*, Kim DH, Park KR, Yun HM, Lee NJ, Lee HP, Shim JH, Jeong HS, Lee YH, Ham YW, Han SB, Hong JT. (E)-2,4-Bis(p-hydroxyphenyl)-2-butenal inhibits tumor growth via suppression of NF-κB and induction of death receptor 6. Apoptosis.19(1):165-178, 2014 (*equal contribution)

24. Jung YS, Kim SJ, Kwon DY, Ahn CW, Kim YS, Choi DW, Kim YC. Alleviation of alcoholic liver injury by betaine involves an enhancement of antioxidant defense via regulation of sulfur amino acid metabolism. Food Chem Toxicol. 62:292-298, 2013

25. Kwon do Y, Jung YS, Kim SJ, Kim YS, Choi DW, Kim YC. Alterations in sulfur amino Acid metabolism in mice treated with silymarin: a novel mechanism of its action involved in enhancement of the antioxidant defense in liver. Planta Med.79(12):997-1002, 2013

26. Jung YS, Kim SJ, Kwon do Y, Jun DS, Kim YC. Significance of alterations in the metabolomics of sulfur-containing amino acids during liver regeneration. Biochimie. 95(8):1605-1610, 2013

27. Jung YS, Yun KU, Ryu CS, Oh JM, Kwak HC, Lee JY, Park SK, Kim BH, Oh SJ, Kim SK. Alterations in hepatic metabolism of sulfur amino acids in non-obese type-2 diabetic Goto-Kakizaki rats. Chem Biol Interact.204(2):80-87, 2013

28. Jung YS, Kato I, Kim HR. A novel function of HPV16-E6/E7 in epithelial-mesenchymal transition. Biochem Biophys Res Commun.435(3):339-344, 2013