학력 Education        

1993     공학학사 (연세대학교 생명공학과) 
1997     공학석사 (연세대학교 생명공학과) 
2002     이학박사 (미국 켄터키 주립대학교 - 해부 및 신경생물학)   
 
 경력 Experience

1997 - 1998   미국 텍사스 주립 대학교 연구원 
2000 - 2002   미국 국립보건원 노화연구소 (NIH/NIA/GRC) 연구원 
2002 - 2004   미국 캘리포니아 주립 대학교 선임연구원 
2004 - 2008   부산대학교 약학대학 약학과 조교수 
2004 - 현재     부산대학교 장수생명과학기술연구원 노화제어실장 
2005 - 현재     부산대학교 신약개발연구소 자원개발부장 
2007 - 현재     대한퇴행성신경질환학회 연구이사 
2007 - 현재     대한약학회 영문학술지(Archives of Pharmacal Research) 편집간사 
2008 - 2010   한국노화학회 국제위원장 
2008 - 2013   부산대학교 약학대학 약학과 부교수 
2009 - 2011   부산대학교 약학대학 약학과 학과장 
2010 - 2011   한국 노화학회 총무 
2010 - 2011   부산대학교 약학대학 부학장   
2011 - 2012   부산대학교 산학협력단 기획연구부장 
2011 - 현재     한국노화학회 운영위원장  
2011 - 현재     Editorial Board, NeuroMolecular Medicine (IF=5.000)  
2013 - 현재     부산대학교 약학대학 약학과 교수
2013 - 2014   미국 국립보건원 노화연구소 (NIH/NIA/GRC)  방문교수
2015 - 현재     대한약학회 영문학술지(Archives of Pharmacal Research) 편집간사
2019 - 2020   부산대학교 대외교류본부 부본부장

2020 - 현재     부산대학교 약학대학 학장

  관심분야

1)  뇌 노화 및 노화관련 퇴행성 신경질환의 분자적 기전

2) 퇴행성 신경질환 제어 연구

3) 성숙된 뇌에 내재하는 신경재생성(adult neurogenesis)의 분자적 기전 및 독성 연구

4) 중추신경계 및 신경질환에 있어서 mitochondria의 중요성

 연구업적 Achievements           

1. Cytotoxicity of 1,2-diacetylbenzene in human neuroblastoma SHSY5Y cells is mediated by oxidative stress. Kim MS, Kim MK, Kim KS, Chung JH, Kim SJ, Kim JH, Kim JR, Lee J, Yu BP, Chung HY. Toxicology. 2008 Jan 14;243(1-2):216-23. 

2. Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus. Kim SJ, Son TG, Park HR, Park M, Kim MS, Kim HS, Chung HY, Mattson MP, Lee J. J Biol Chem. 2008 May 23;283(21):14497-505. 

3. Mitochondrial ATP synthase is a target for TNBS-induced protein carbonylation in XS-106 dendritic cells. Je JH, Lee TH, Kim DH, Cho YH, Lee JH, Kim SC, Lee SK, Lee J, Lee MG. Proteomics. 2008 Jun;8(12):2384-93.

4. Cytoprotective roles of senescence marker protein 30 against intracellular calcium elevation and oxidative stress. Son TG, Kim SJ, Kim K, Kim MS, Chung HY, Lee J.Arch Pharm Res.2008 Jul;31(7):872-7. 

5. Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice. Kondo Y, Sasaki T, Sato Y, Amano A, Aizawa S, Iwama M, Handa S, Shimada N, Fukuda M, Akita M, Lee J, Jeong KS, Maruyama N, Ishigami A. Biochem Biophys Res Commun. 2008 Dec 5;377(1):291-6. 

6. Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta- catenin signaling. Piao S, Lee SH, Kim H, Yum S, Stamos JL, Xu Y, Lee SJ, Lee J, Oh S, Han JK, Park BJ, Weis WI, Ha NC. PLoS One. 2008;3(12):e4046.

7. 2-Deoxy-d-glucose protects neural progenitor cells against oxidative stress through the activation of AMP-activated protein kinase. Park M, Song KS, Kim HK, Park YJ, Kim HS, Bae MI, Lee J. Neurosci Lett. 2009 Jan 16;449(3):201-6. 

8. Mee Young AHN, Yong Jin NA, Jaewon LEE, Byung Mu LEE, Hyung Sik KIM (2009) Apicidin induces apoptosis via cytochrome c-mediated intrinc pathway in human ovarian cancer cells. Biomolecules & Therapeutics, 17(1):17-24.

9. The role of the Ser/Thr cluster in the phosphorylation of PPPSP motifs in Wnt coreceptors. Yum S, Lee SJ, Piao S, Xu Y, Jung J, Jung Y, Oh S, Lee J, Park BJ, Ha NC. Biochem Biophys Res Commun. 2009 Apr 10;381(3):345-9.

10. Mechanism of apicidin-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells. Ahn MY, Lee J, Na YJ, Choi WS, Lee BM, Kang KW, Kim HS. Chem Biol Interact. 2009 May 15;179(2-3):169-77. 

11. Adenine nucleotide translocator 1 deficiency increases resistance of mouse brain and neurons to excitotoxic insults. Lee J, Schriner SE, Wallace DC. Biochim Biophys Acta. 2009 May;1787(5):364-70. 

12. Neurotoxic effect of 2,5-hexanedione on neural progenitor cells and hippocampal neurogenesis. Kim MS, Park HR, Park M, Kim SJ, Kwon M, Yu BP, Chung HY, Kim HS, Kwack SJ, Kang TS, Kim SH, Lee J. Toxicology. 2009 Jun 16;260(1-3):97-103. 

13. Revealing system-level correlations between aging and calorie restriction using a mouse transcriptome. Hong SE, Heo HS, Kim DH, Kim MS, Kim CH, Lee J, Yoo MA, Yu BP, Leeuwenburgh C, Chung HY. Age (Dordr). 2010 Mar;32(1):15-30. 

14. The anti-inflammatory effect of kaempferol in aged kidney tissues: the involvement of nuclear factor-kappaB via nuclear factor-inducing kinase/IkappaB kinase and mitogen-activated protein kinase pathways. Park MJ, Lee EK, Heo HS, Kim MS, Sung B, Kim MK, Lee J, Kim ND, Anton S, Choi JS, Yu BP, Chung HY. J Med Food. 2009 Apr;12(2):351-8.

15. Senescence marker protein 30 is up-regulated in kainate-induced hippocampal damage through ERK-mediated astrocytosis. Son TG, Park HR, Kim SJ, Kim K, Kim MS, Ishigami A, Handa S, Maruyama N, Chung HY, Lee J. J Neurosci Res. 2009 Oct;87(13):2890-7

16. Risk assessment for the combinational effects of food color additives: neural progenitor cells and hippocampal neurogenesis. Park M, Park HR, Kim SJ, Kim MS, Kong KH, Kim HS, Gong EJ, Kim ME, Kim HS, Lee BM, Lee J. J Toxicol Environ Health A. 2009;72(21-22):1412-23.

17. Potencies of bisphenol A on the neuronal differentiation and hippocampal
neurogenesis. Kim K, Son TG, Park HR, Kim SJ, Kim HS, Kim HS, Kim TS, Jung KK, Han SY, Lee J. J Toxicol Environ Health A. 2009;72(21-22):1343-51. 

18. Exposure assessment of polybrominated diphenyl ethers (PBDE) in umbilical cord blood of Korean infants. Kim TH, Lee YJ, Lee E, Patra N, Lee J, Kwack SJ, Kim KB, Chung KK, Han SY, Han JY, Lee BM, Kim HS. J Toxicol Environ Health A. 2009;72(21-22):1318-26.

19. Effects of gestational exposure to decabromodiphenyl ether on reproductive parameters, thyroid hormone levels, and neuronal development in Sprague-Dawley rats offspring. Kim TH, Lee YJ, Lee E, Kim MS, Kwack SJ, Kim KB, Chung KK, Kang TS, Han SY, Lee J, Lee BM, Kim HS. J Toxicol Environ Health A. 2009;72(21-22):1296-303.

20. Acrylamide induces cell death in neural progenitor cells and impairs hippocampal neurogenesis. Park HR, Kim MS, Kim SJ, Park M, Kong KH, Kim HS, Kwack SJ, Kang TS, Kim SH, Kim HS, Lee J. Toxicol Lett. 2010 Mar 1;193(1):86-93. 

21. Developmental and age-related changes of peptidylarginine deiminase 2 in the mouse brain. Shimada N, Handa S, Uchida Y, Fukuda M, Maruyama N, Asaga H, Choi EK, Lee J, Ishigami A. J Neurosci Res. 2010 Mar;88(4):798-806. 

22. Capsaicin impairs proliferation of neural progenitor cells and hippocampal neurogenesis in young mice. Kong KH, Kim HK, Song KS, Woo YS, Choi WS, Park HR, Park M, Kim ME, Kim MS, Ryu JS, Kim HS, Lee J. J Toxicol Environ Health A. 2010; 73(21-22):1490-501.

23. Evaluation of liver and thyroid toxicity in Sprague-Dawley rats after exposure to polybrominated diphenyl ether BDE-209. Lee E, Kim TH, Choi JS, Nabanata P, Kim NY, Ahn MY, Jung KK, Kang IH, Kim TS, Kwack SJ, Park KL, Kim SH, Kang TS, Lee J, Lee BM, Kim HS. J Toxicol Sci. 2010;35(4):535-45.

24. A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor. Park HR, Park M, Choi J, Park KY, Chung HY, Lee J. Neurosci Lett. 2010 Oct 4;482(3):235-9. 

25. Molecular delineation of gamma-ray-induced NF-kappaB activation and pro-inflammatory genes in SMP30 knockout mice. Chung SW, Kim JM, Kim DH, Kim JY, Lee EK, Anton S, Jeong KS, Lee J, Yoo MA, Kim YJ, Yu BP, Chung HY. Radiat Res. 2010 May;173(5):629-34.

26. Functional role of phospholipase D (PLD) in di(2-ethylhexyl) phthalate-induced hepatotoxicity in Sprague-Dawley rats. Kim NY, Kim TH, Lee E, Patra N, Lee J, Shin MO, Kwack SJ, Park KL, Han SY, Kang TS, Kim SH, Lee BM, Kim HS. J Toxicol Environ Health A. 2010;73(21-22):1560-9.

27. A novel epoxypropoxy flavonoid derivative and topoisomerase II inhibitor, MHY336, induces apoptosis in prostate cancer cells. Patra N, De U, Kang JA, Kim JM, Ahn MY, Lee J, Jung JH, Chung HY, Moon HR, Kim HS. Eur J Pharmacol. 2011 May 11;658(2-3):98-107. 

28. Hyperoxia attenuates the inhibitory effect of nitric oxide donors on HIF prolyl-4-hydroxylase-2: Implication on discriminative effect of nitric oxide on HIF prolyl-4-hydroxylase-2 and collagen prolyl-4-hydroxylase. Yum S, Choi J, Hong S, Park MH, Lee J, Ha NC, Jung Y. Biochem Pharmacol. 2011 Sep 1;82(5):485-90. 

29. Morin attenuates tau hyperphosphorylation by inhibiting GSK3 β . Gong EJ, Park HR, Kim ME, Piao S, Lee E, Jo DG, Chung HY, Ha NC, Mattson MP, Lee J. Neurobiol Dis. 2011 Nov;44(2):223-30. 

30. Neurogenic contributions made by dietary regulation to hippocampal neurogenesis. Park HR, Lee J. Ann N Y Acad Sci. 2011 Jul;1229(1):23-8.

31. Lipotoxicity of Palmitic Acid on Neural Progenitor Cells and Hippocampal Neurogenesis. Park HR, Kim JY. Park KY, Lee J. Toxicological Research, 2011 Jun; 27(2):103-110. 

32. Exposure to bisphenol A appears to impair hippocampal neurogenesis and spatial learning and memory. Kim ME, Park HR, Gong EJ, Choi SY, Kim HS, Lee J. Food Chem Toxicol. 2011 Dec;49(12):3383-9

33. A new synthetic HDAC inhibitor, MHY218, induces apoptosis or autophagy-related cell death in tamoxifen-resistant MCF-7 breast cancer cells. Park JH, Ahn MY, Kim TH, Yoon S, Kang KW, Lee J, Moon HR, Jung JH, Chung HY, Kim HS. Invest New Drugs. 2011 Oct 8. [Epub ahead of print]

34. Organic solvent metabolite, 1,2-diacetylbenzene, impairs neural progenitor cells and hippocampal neurogenesis. Kim MS, Park HR, Chung HY, Kim HS, Yu BP, Yang HS, Lee J. Chem Biol Interact. 2011 Nov 15;194(2-3):139-47.

35. The hepatoprotective effects of adenine nucleotide translocator-2 against aging and oxidative stress. Kim HS, Je JH, Son TG, Park HR, Ji ST, Pokharel YR, Jeon HM, Kang KW, Kang HS, Chang SC, Kim HS, Chung HY, Lee J. Free Radic Res. 2012 Jan;46(1):21-9.

36. Chemopreventive mechanisms of methionine on inhibition of benzo(a)pyrene-DNA adducts formation in human hepatocellular carcinoma HepG2 cells. Roh T, Kwak MY, Kwak EH, Kim DH, Han EY, Bae JY, Bang du Y, Lim DS, Ahn IY, Jang DE, Lim SK, Yoo SD, Kwack SJ, Park KL, Lee YJ, Kim KB, Lee J, Kim HS, Lee BM. Toxicol Lett. 2012 Feb 5;208(3):232-8. 

37. Comparisons of polybrominated diphenyl ethers levels in paired South Korean cord blood, maternal blood, and breast milk samples. Kim TH, Bang du Y, Lim HJ, Won AJ, Ahn MY, Patra N, Chung KK, Kwack SJ, Park KL, Han SY, Choi WS, Han JY, Lee BM, Oh JE, Yoon JH, Lee J, Kim HS. Chemosphere. 2012 Mar;87(1):97-104.

38. High dose bisphenol A impairs hippocampal neurogenesis in female mice across generations. Jang YJ, Park HR, Kim TH, Yang WJ, Lee JJ, Choi SY, Oh SB, Lee E, Park JH, Kim HP, Kim HS, Lee J. Toxicology. 2012 Jun 14;296(1-3):73-82.

39. Naphthazarin has a protective effect on the 1-methyl-4-phenyl-1,2,3,4-tetrahydropyridine-induced Parkinson's disease model. Choi SY, Son TG, Park HR, Jang YJ, Oh SB, Jin B, Lee J. J Neurosci Res. 2012 Sep;90(9):1842-9.

40. Oxidative lipid modification of nicastrin enhances amyloidogenic  γ -secretase activity in Alzheimer's disease.Gwon AR, Park JS, Arumugam TV, Kwon YK, Chan SL, Kim SH, Baik SH, Yang S, Yun YK, Choi Y, Kim S, Tang SC, Hyun DH, Cheng A, Dann CE 3rd, Bernier M, Lee J, Markesbery WR, Mattson MP, Jo DG. Aging Cell. 2012 Mar 10. doi: 10.1111/j.1474-9726.2012.00817.x. [Epub ahead of print]

41. Baicalein attenuates impaired hippocampal neurogenesis and the neurocognitive deficits induced by γ-ray radiation. Oh SB, Park HR, Jang YJ, Choi SY, Son TG, Lee J. Br J Pharmacol. 2013 Jan;168(2):421-31.

42. Selective impairment on the proliferation of neural progenitor cells by oxidative phosphorylation disruption. Lee Y, Oh SB, Park HR, Kim HS, Kim MS, Lee J. Neurosci Lett. 2013 Feb 22;535:134-9.

43. Senescence marker protein 30 deficiency increases Parkinson's pathology by impairing astrocyte activation. Kim HS, Son TG, Park HR, Lee Y, Jung Y, Ishigami A, Lee J. Neurobiol Aging. 2013 Apr;34(4):1177-83.

44. Insufficient ascorbic acid intake during gestation induces abnormal cardiac dilation in fetal and neonatal SMP30/GNL knockout mice. Kishimoto Y, Kanai T, Sato K, Lee J, Jeong KS, Shimokado K, Maruyama N, Ishigami A. Pediatr Res. 2013 May;73(5):578-84.

45. Development of Akt-activated GSK3β inhibitory peptide. Kim JS, Piao S, Lee E, Yoon BY, Moon HR, Lee J, Jung Y, Ha NC. Biochem Biophys Res Commun. 2013 May 17;434(4):735-9.

46. Elevated TRAF2/6 expression in Parkinson's disease is caused by the loss of Parkin E3 ligase activity. Chung JY, Park HR, Lee SJ, Lee SH, Kim JS, Jung YS, Hwang SH, Ha NC, Seol WG, Lee J, Park BJ. Lab Invest. 2013 Jun;93(6):663-76.

47. Diallyl disulfide impairs hippocampal neurogenesis in the young adult brain. Ji ST, Kim MS, Park HR, Lee E, Lee Y, Jang YJ, Kim HS, Lee J. Toxicol Lett. 2013 Jul 31;221(1):31-8.

48. Recent advances in calorie restriction research on aging. Chung KW, Kim DH, Park MH, Choi YJ, Kim ND, Lee J, Yu BP, Chung HY. Exp Gerontol. 2013 Oct;48(10):1049-53.

49. Baicalein attenuates astroglial activation in the 1-methyl-4-phenyl-1,2,3,4-tetrahydropyridine-induced Parkinson's disease model by downregulating the activations of nuclear factor-κB, ERK, and JNK. Lee E, Park HR, Ji ST, Lee Y, Lee J. J Neurosci Res. 2014 Jan;92(1):130-9.

50. Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system. Lee J, Jo DG, Park D, Chung HY, Mattson MP. Pharmacol Rev. 2014 Jul;66(3):815-68.

51. Sphingosine 1-phosphate induced anti-atherogenic and atheroprotective M2 macrophage polarization through IL-4. Park SJ, Lee KP, Kang S, Lee J, Sato K, Chung HY, Okajima F, Im DS. Cell Signal. 2014 Oct;26(10):2249-58.

52. Viriditoxin regulates apoptosis and autophagy via mitotic catastrophe and microtubule formation in human prostate cancer cells. Kundu S, Kim TH, Yoon JH, Shin HS, Lee J, Jung JH, Kim HS. Int J Oncol. 2014 Dec;45(6):2331-40.

53. Age-related inflammation and insulin resistance: a review of their intricate interdependency. Park MH, Kim DH, Lee EK, Kim ND, Im DS, Lee J, Yu BP, Chung HY. Arch Pharm Res. 2014 Dec;37(12):1507-14.

54. Evaluation of cadmium-induced nephrotoxicity using urinary metabolomic profiles in sprague-dawley male rats. Lee YK, Park EY, Kim S, Son JY, Kim TH, Kang WG, Jeong TC, Kim KB, Kwack SJ, Lee J, Kim S, Lee BM, Kim HS. J Toxicol Environ Health A. 2014;77(22-24):1384-98.

55. Transformation of Mouse Liver Cells by Methylcholanthrene Leads to Phenotypic Changes Associated with Epithelial-mesenchymal Transition. Oh J, Kwak JH, Kwon DY, Kim AY, Oh DS, Je NK, Lee J, Jung YS. Toxicol Res. 2014 Dec;30(4):261-6.

56. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Kim TH, Kim HS, Kang YJ, Yoon S, Lee J, Choi WS, Jung JH, Kim HS. Biochim Biophys Acta. 2015 Feb;1850(2):401-10.

57. Silibinin prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease via mitochondrial stabilization. Lee Y, Park HR, Chun HJ, Lee J. J Neurosci Res. 2015 May;93(5):755-65.

58. Neuroprotection and spatial memory enhancement of four herbal mixture extract in HT22 hippocampal cells and a mouse model of focal cerebral ischemia. Ahn SM, Kim YR, Kim HN, Choi YW, Lee JW, Kim CM, Baek JU, Shin HK, Choi BT. BMC Complement Altern Med. 2015 Jun 30;15:202

59. PMC-12, a Prescription of Traditional Korean Medicine, Improves Amyloid β-Induced Cognitive Deficits through Modulation of Neuroinflammation. Park MY, Jung YS, Park JH, Choi YW, Lee J, Kim CM, Baek JU, Choi BT, Shin HK. Evid Based Complement Alternat Med. 2015;2015:768049

60. Colon-targeted delivery of budesonide using dual pH- and time-dependent polymeric nanoparticles for colitis therapy. Naeem M, Choi M, Cao J, Lee Y, Ikram M, Yoon S, Lee J, Moon HR, Kim MS, Jung Y, Yoo JW. Drug Des Devel Ther. 2015 Jul 21;9:3789-99.

61. Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome/IL-1β for steatohepatitis. Chung KW, Lee EK, Kim DH, An HJ, Kim ND, Im DS, Lee J, Yu BP, Chung HY. Aging Cell. 2015 Aug;14(4):524-33.

62. The mitochondrial uncoupler DNP triggers brain cell mTOR signaling network reprogramming and CREB pathway up-regulation. Liu D, Zhang Y, Gharavi R, Park HR, Lee J, Siddiqui S, Telljohann R, Nassar MR, Cutler RG, Becker KG, Mattson MP. J Neurochem. 2015 Aug;134(4):677-92

63. Silibinin suppresses astroglial activation in a mouse model of acute Parkinson?s disease by modulating the ERK and JNK signaling pathways. Lee Y, Chun HJ, Lee KM, Jung YS, Lee J. Brain Res. 2015 Nov 19;1627:233-42.

64. PMC-12, a traditional herbal medicine, enhances learning memory and hippocampal neurogenesis in mice. Park HR, Kim JY, Lee Y, Chun HJ, Choi YW, Shin HK, Choi BT, Kim CM, Lee J. Neurosci Lett. 2016 Mar 23;617:254-63.

65. Methylglyoxal Causes Cell Death in Neural Progenitor Cells and Impairs Adult Hippocampal Neurogenesis. Chun HJ, Lee Y, Kim AH, Lee J. Neurotox Res. 2016 Apr;29(3):419-31.

66. Stable and biocompatible cystine knot peptides from the marine sponge Asteropus sp. Su M, Li H, Wang H, Kim EL, Kim HS, Kim EH, Lee J, Jung JH. Bioorg Med Chem. 2016 Jul 1;24(13):2979-87.

67. Neuroprotective and anti-inflammatory effects of morin in a murine model of Parkinson's disease. Lee KM, Lee Y, Chun HJ, Kim AH, Kim JY, Lee JY, Ishigami A, Lee J. J Neurosci Res. 2016 Oct;94(10):865-78.

68. Neuroprotective effect of bee venom is mediated by reduced astrocyte activation in a subchronic MPTP-induced model of Parkinson's disease. Kim ME, Lee JY, Lee KM, Park HR, Lee E, Lee Y, Lee JS, Lee J. Arch Pharm Res. 2016 Aug;39(8):1160-70.

69. Tyrosinase inhibitory flavonoid from Juniperus communis fruits. Jegal J, Park SA, Chung K, Chung HY, Lee J, Jeong EJ, Kim KH, Yang MH. Biosci Biotechnol Biochem. 2016 Dec;80(12):2311-2317

70. Anticancer Effects of a New SIRT Inhibitor, MHY2256, against Human Breast Cancer MCF-7 Cells via Regulation of MDM2-p53 Binding. Park EY, Woo Y, Kim SJ, Kim DH, Lee EK, De U, Kim KS, Lee J, Jung JH, Ha KT, Choi WS, Kim IS, Lee BM, Yoon S, Moon HR, Kim HS. Int J Biol Sci. 2016 Dec 6;12(12):1555-1567. eCollection 2016.

71. Neuroprotective effects of 2,4-dinitrophenol in an acute model of Parkinson's disease. Lee Y, Heo G, Lee KM, Kim AH, Chung KW, Im E, Chung HY, Lee J. Brain Res. 2017 May 15;1663:184-193. doi: 10.1016/j.brainres.2017.03.018. Epub 2017 Mar 18.

72. miR-10a and miR-204 as a Potential Prognostic Indicator in Low-Grade Gliomas. Son JC, Jeong HO, Park D, No SG, Lee EK, Lee J, Chung HY. Cancer Inform. 2017 Apr 12;16:1176935117702878.

73. High dose tetrabromobisphenol A impairs hippocampal neurogenesis and memory retention. Kim AH, Chun HJ, Lee S, Kim HS, Lee J. Food Chem Toxicol. 2017 Aug;106(Pt A):223-231.

74. The critical role played by endotoxin-induced liver autophagy in the maintenance of lipid metabolism during sepsis. Chung KW, Kim KM, Choi YJ, An HJ, Lee B, Kim DH, Lee EK, Im E, Lee J, Im DS, Yu BP, Chung HY. Autophagy. 2017 Jul 3;13(7):1113-1129.

75. Identification of a sensitive urinary biomarker, selenium-binding protein 1, for early detection of acute kidney injury. Kim KS, Yang HY, Song H, Kang YR, Kwon J, An J, Son JY, Kwack SJ, Kim YM, Bae ON, Ahn MY, Lee J, Yoon S, Lee BM, Kim HS. J Toxicol Environ Health A. 2017;80(9):453-464.

76. Time-Dependent Alterations of Vancomycin-Induced Nephrotoxicity in Mice. Takigawa M, Masutomi H, Kishimoto Y, Shimazaki Y, Hamano Y, Kondo Y, Arai T, Lee J, Ishii T, Mori Y, Ishigami A. Biol Pharm Bull. 2017;40(7):975-983.

77. Neuroprotective strategies to prevent and treat Parkinson’s disease based on its pathophysiological mechanism. Lee, Y.,Kim, M.-S.,Lee, J. Archives of Pharmacal Research, 2017 Oct;40(10):1117-1128.

78. One-step construction of a molybdenum disulfide/multi-walled carbon nanotubes/polypyrrole nanocomposite biosensor for the ex-vivo detection of dopamine in mouse brain tissue. Vijayaraj K, Dinakaran T, Lee Y, Kim S, Kim HS, Lee J, Chang SC. Biochem Biophys Res Commun. 2017 Dec 9;494(1-2):181-187.

79. Transformation of liver cells by 3-methylcholanthrene potentiates oxidative stress via the downregulation of glutathione synthesis. Kim SH, Yoon D, Lee YH, Lee J, Kim ND, Kim S, Jung YS. Int J Mol Med. 2017 Oct 11. doi: 10.3892/ijmm.2017.3184. [Epub ahead of print]

80. Electrochemical reactive oxygen species detection by cytochrome c immobilized with vertically aligned and electrochemically reduced graphene oxide on a glassy carbon electrode. Thirumalai D, Kathiresan V, Lee J, Jin SH, Chang SC. Analyst. 2017 Nov 20;142(23):4544-4552.

81. Transformation of liver cells by 3-methylcholanthrene potentiates oxidative stress via the downregulation of glutathione synthesis. Kim SH, Yoon D, Lee YH, Lee J, Kim ND, Kim S, Jung YS. Int J Mol Med. 2017 Dec;40(6):2011-2017

82. Electrochemical reactive oxygen species detection by cytochrome c immobilized with vertically aligned and electrochemically reduced graphene oxide on a glassy carbon electrode. Thirumalai D, Kathiresan V, Lee J, Jin SH, Chang SC. Analyst. 2017 Nov 20;142(23):4544-4552.

83. Curcumin ameliorates cadmium-induced nephrotoxicity in Sprague-Dawley rats. Kim KS, Lim HJ, Lim JS, Son JY, Lee J, Lee BM, Chang SC, Kim HS. Food Chem Toxicol. 2018 Apr;114:34-40.

84. Learning, memory deficits, and impaired neuronal maturation attributed to acrylamide. Lee S, Park HR, Lee JY, Cho JH, Song HM, Kim AH, Lee W, Lee Y, Chang SC, Kim HS, Lee J. J Toxicol Environ Health A. 2018;81(9):254-265.

85. Hepatic damage exacerbates cisplatin-induced acute kidney injury in Sprague-Dawley rats. Kim JS, Son JY, Kim KS, Lim HJ, Ahn MY, Kwack SJ, Kim YM, Lee KY, Lee J, Lee BM, Kim HS. J Toxicol Environ Health A. 2018;81(11):397-407.

86. Sensitive neurotoxicity assessment of bisphenol A using double immunocytochemistry of DCX and MAP2. Cho JH, Kim AH, Lee S, Lee Y, Lee WJ, Chang SC, Lee J. Arch Pharm Res. 2018 Nov;41(11):1098-1107.

87. Neuroprotective effects of MHY908, a PPAR α/γ dual agonist, in a MPTP-induced Parkinson's disease model. Lee Y, Cho JH, Lee S, Lee W, Chang SC, Chung HY, Moon HR, Lee J. Brain Res. 2018 Sep 28. pii: S0006-8993(18)30501-8.

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