학력 Education

1989. 02     부산대학교 약학대학 제약학과 (학사)
1991. 02     서울대학교 대학원 약학과 (석사)
1991. 05     서울대학교 대학원 약학과(박사)

 경력 Experience

1997 - 1999     이화여자대학교 약학대학 Post-Doc
1997 - 1998     이화여자대학교 약학대학 시간강사
1998 - 1999     이화여자대학교 약학대학 시간강사
1999 - 2001     Lab. of Medicinal Chemistry, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, USA, Post-Doc.
2001 - 2001     이화여자대학교 약학대학 Post-Doc.
2001 - 2001     건국대학교 시간강사
2001 - 2001     이화여자대학교 약학대학 시간강사
2001 - 2002     숙명여자대학교 약학대학 시간강사
2001 - 2003     이화여자대학교 약학연구소 연구 전임강사
2003 - 2007       부산대학교 약학대학 약학부 조교수

2007 - 2012       부산대학교 약학대학 약학부 부교수

2012 - 현재         부산대학교 약학대학 약학부 교수

 연구 테마  

1. 화장품 분야: 피부 미백제 및 주름 개선제 개발
2. 의약품 분야:
- 심혈관계 질환 치료제 : PPAR alpha agonist 및 alpha/gamma dual agonist 개발
- 당뇨병 치료제 : PPAR gamma agonist 및 alpha/gamma dual agonist 개발
- 수명연장 약물 : Sirt activator 개발
- 항암제 : HDAC 저해제 개발
               DNA intercalator 개발
               topoisomerase 저해제 개발
               EGFR, VEGFR 저해제 개발 ----표적항암제
               Sirt 저해제 개발

 대학원생 선발   

- 대학교에서 유기화학을 이수한 졸업생 중에서 선발.

- 화장품이나 의약품 합성 및 개발에 관심이 있는 졸업생 선발.

  
 연구업적 Achievements     

Patents(특허)

국외 등록(Patent Registration overseas)
- 피부미백, 항산화 및 PPAR활성을 갖는 신규화합물 및 이의 의학적 용도, 9,155,69  (2015.10.13), USA
- 피부미백, 항산화 및 PPAR 활성을 갖는 신규 화합물 및 이의 의학적 용도, 9,216,148(2015.12.22), USA
- 피부미백, 항산화 및 PPAR활성을 갖는 신규화합물 및 이의 의학적 용도, 8,889,881(2014.11.18), USA
- 피부미백, 항산화 및 PPAR 활성을 갖는 신규 화합물 및 이의 의학적 용도, 6000981(2016.09.09), JP
- 피부미백, 항산화 및 PPAR활성을 갖는 신규화합물 및 이의 의학적 용도, 5856186(2015.12.18), JP

국외 출원(Patent Application overseas)
- NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF, 14/973,752(2015.12.18), USA
- NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF, 14/838,381(2015.08.28), USA
- 피부미백, 항산화 및 PPAR활성을 갖는 신규화합물 및 이의 의학적 용도, 2015-24117(2015.12.10), JP
- TLR4에 LPS와의 경쟁적 결합을 통한 항산화 및 항염증 활성을 갖는 신규 화합물 및 이의 의학적 용도, PCT/KR2015/007655(2015.07.23), PCT
- 피부미백,항산화 및 PPAR 활성을 갖는 신규 화합물 및 이의 의학적 용도, PCT/KR2012/000899(2012.02.08),PCT
- 피부미백, 항산화 및 PPAR활성을 갖는 신규화합물 및 이의 의학적 용도, PCT/KR2012/000935(2012.02.08),PCT
- 피부미백,항산화 및 PPAR 활성을 갖는 신규 화합물 및 이의 의학적 용도, PCT/KR2012/000898(2012.02.08),PCT
- Synthesis and Biological Evaluations of SAHA and Psammaplin A Derivatives as Potenitial HDAC inhibitors, 61/296,756(2010.01.20), USA

국내 등록(Domestic Patent Registration)
- 바비투르산 및 싸이오바비투르산 유도체를 유효성분으로 함유하는 발모촉진용 조성물, 10-1732929(2017.04.27)
- (Ｚ)―２―아세트아미도―３―(４―히드록시―３―메톡시 페닐)아크릴산을 유효성분으로포함하는 암 예방 또는 치료용 조성물, 10-1724425(2017.04.03)
- (Ｚ)―５―(４―히드록시―３,５―디메톡시벤질리덴)―２―티옥소이미다졸리딘―４―온)을 유효성분으로 포함하는 암 예방 또는 치료용 조성물, 10-1699659(2017.01.18)
- TLR4에 LPS와의 경쟁적 결합을 통한 항산화 및 항염증 활성을 갖는 신규 화합물 및 이의 의학적 용도, 0-1686872(2016.12.09)
- 피부미백 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-1677121(2016.11.11)
- 피부미백, 항산화 및 ＰＰＡＲ 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-1677122(2016.11.11)
- 피부미백 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-1475590(2014.12.16)
- 피부미백 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-1527100(2015.06.02)
- 피부미백 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-1488583(2015.01.26)
- 피부미백 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-1449831(2014.10.02)
- 피부미백 및 ＰＰＡＲ 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-1292478(2013.07.26)
- 피부미백, 항산화 및 ＰＰＡＲ 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-1366372(2014.02.17)
- 피부미백, 항산화 및 ＰＰＡＲ 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-1334579(2013.11.22)
- 피부미백, 항산화 및 ＰＰＡＲ 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-1411838(2014.06.19)
- 피부미백, 항산화 및 ＰＰＡＲ 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-1395146(2014.05.08)
- 피부미백, 항산화 및 ＰＰＡＲ 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-1334466(2013.11.22)

국내 출원(Domestic Patent Application)
- (Z)-5-(2,4-디하이드록시벤질리덴)티아졸리딘-2,4-디온을 유효성분으로 포함하는 간 손상 보 호용 조성물, 10-2017-0076645(2017.06.16)
- 신규 Sirt1 활성화제 의학적 용도, 10-2017-0049956(2017.04.18)
- 신경염증제어를 통한 파킨슨 질환 예방 또는 치료용 조성물, 10-2017-0045262(2017.04.07)
- PPAR, FXR 및 AMPK 활성화 효능을 갖는 신규 티오펜 화합물 또는 이의 약제학적으로 허용 가 능한 염 및 이의 의학적 용도, 10-2017-0015080(2017.02.02)
- MHY498을 유효성분으로 함유하는 피부미백용 고형 지질 나노입자 조성물 및 이의 제조방법, 10-2016-0117284(2016.09.12)
- PPAR 효능제로서 벤조티아졸릴 및 벤조이미다졸릴 디플루오로아세트산 유도체 및 이의 의학적 용도, 10-2016-0039082(2016.03.31)
- 신규 SIRT-1 활성제인 MHY2746의 용도, 10-2016-0039085(2016.03.31)
- ＰＰＡＲ 및 ＦＸＲ 활성화 효능을 갖는 신규 티오펜 화합물 또는 이의 약제학적으로 허용가능한 염 및 이의 의학적 용도, 10-2016-0012823(2016.02.02)
- 피부미백, 항산화 및 PPAR활성을 갖는 신규화합물 및 이의 의학적 용도, 2015-241177 (2015.12.10)
- 피부미백, 항산화 및 PPAR활성을 갖는 신규화합물 및 이의 의학적 용도, 10-2015-0165453(2015.11.25)
- TLR4에 LPS와의 경쟁적 결합을 통한 항산화 및 항염증 활성을 갖는 신규 화합물 및 이의 의학적 용도, 10-2014-0110853(2014.08.25)

Papers published

191. Design of balanced COX inhibitors based on anti-inflammatory and/or COX-2 inhibitory ascidian metabolites. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2019-10

190. Pro-apoptotic effect of the novel benzylidene derivative MHY695 in human colon cancer cells. ONCOLOGY LETTERS, SPANDIDOS PUBL LTD, 2019-09

189. Inhibitory effects of N-(acryloyl)benzamide derivatives on tyrosinase and melanogenesis. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2019-09

188. In vitro and in vivo evidence of tyrosinase inhibitory activity of a synthesized (Z)-5-(3-hydroxy-4-methoxybenzylidene)-2-thioxothiazolidin-4-one (5-HMT). EXPERIMENTAL DERMATOLOGY, BLACKWELL MUNKSGAARD, 2019-06

187. Antioxidant, anti-tyrosinase and anti-melanogenic effects of (E)-2,3-diphenylacrylic acid derivatives. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2019-06

186. Tyrosinase inhibition and anti-melanin generation effect of cinnamamide analogues. BIOORGANIC CHEMISTRY, ACADEMIC PRESS INC ELSEVIER SCIENCE,

2019-06

185. MHY2233 Attenuates Replicative Cellular Senescence in Human Endothelial Progenitor Cells via SIRT1 Signaling. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, LANDES BIOSCIENCE, 2019-05

184. Neuroprotective effects of MHY908, a PPAR α/γ dual agonist, in a MPTP-induced Parkinson's disease model. BRAIN RESEARCH, ELSEVIER SCIENCE BV, 2019-02

183. MHY440, a Novel Topoisomerase Inhibitor, Induces Cell Cycle Arrest and Apoptosis via a ROS-Dependent DNA Damage Signaling Pathway in AGS Human Gastric Cancer Cells. MOLECULES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2019-01

182. The tyrosinase-inhibitory effects of 2-phenyl-1,4-naphthoquinone analogs: importance of the (E)--phenyl-,-unsaturated carbonyl scaffold of an endomethylene type. MEDICINAL CHEMISTRY RESEARCH, BIRKHAUSER BOSTON INC, 2019-01

181. Synthesis of cinnamic amide derivatives and their anti-melanogenic effect in alpha-MSH-stimulated B16F10 melanoma cells. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2019-01

180. Evaluation of the Novel Synthetic Tyrosinase Inhibitor (Z)-3-(3-bromo-4-hydroxybenzylidene)thiochroman-4-one (MHY1498) In Vitro and In Silico. MOLECULES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2018-12

179. In vitro and in vivo evaluation of MHY908-loaded nanostructured lipid carriers for the topical treatment of hyperpigmentation. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, EDITIONS SANTE, 2018-12

178. Design, synthesis and anti-melanogenic effect of cinnamamide derivatives. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2018-11

177. A Potent Tyrosinase Inhibitor, (E)-3-(2,4-Dihydroxyphenyl)-1-(thiophen-2-yl)prop-2-en-1-one, with Anti-Melanogenesis Properties in alpha-MSH and IBMX-Induced B16F10 Melanoma Cells. MOLECULES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2018-10

176. Design of PPAR-gamma agonist based on algal metabolites and the endogenous ligand 15-deoxy-Delta(12,) (14)-prostaglandin J(2). EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2018-09

175. A new synthetic histone deacetylase inhibitor, MHY2256, induces apoptosis and autophagy cell death in endometrial cancer cells via p53 acetylation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2018-09

174. Novel β-phenylacrylic acid derivatives exert anti-cancer activity by inducing Src-mediated apoptosis in wild-type KRAS colon cancer. CELL DEATH & DISEASE, NATURE PUBLISHING GROUP, 2018-09

173. Hepatoprotective Effects of MHY3200 on High-Fat, Diet-Induced, Non-Alcoholic Fatty Liver Disease in Rats. MOLECULES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2018-08

172. The tyrosinase inhibitory effects of isoxazolone derivatives with a (Z)-β-phenyl-α, β-unsaturated carbonyl scaffold. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2018-08

171. (2E,5E)-2,5-Bis (3-hydroxy-4-methoxyb enzylidene) cyclopentanone Exerts Anti-Melanogenesis and Anti-Wrinkle Activities in B16F10 Melanoma and Hs27 Fibroblast Cells. MOLECULES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2018-06

170. A novel synthetic compound, (Z)-5-(3-hydroxy-4-methoxybenzylidene)-2-iminothiazolidin-4-one (MHY773) inhibits mushroom tyrosinase. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, JAPAN SOC BIOSCI BIOTECHN AGROCHEM, 2018-05

169. Cytoprotective Roles of a Novel Compound, MHY-1684, against Hyperglycemia-Induced Oxidative Stress and Mitochondrial Dysfunction in Human Cardiac Progenitor Cells. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, LANDES BIOSCIENCE, 2018-05

168. Novel SIRT1 activator MHY2233 improves glucose tolerance and reduces hepatic lipid accumulation in db/db mice. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2018-02

167. Colon-targeted delivery of cyclosporine A using dual-functional Eudragit (R) FS30D/PLGA nanoparticles ameliorates murine experimental colitis. INTERNATIONAL JOURNAL OF NANOMEDICINE, DOVE MEDICAL PRESS LTD, 2018-02

166. A PPAR Pan Agonist, MHY2013 Alleviates Age-Related Hepatic Lipid Accumulation by Promoting Fatty Acid Oxidation and Suppressing Inflammation. BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, 2018-01

165. Evaluation of Antimelanogenic Activity and Mechanism of Galangin in Silico and in Vivo. BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, 2018-01

164. PPARα activation by MHY908 attenuates age-related renal inflammation through modulation of the ROS/Akt/FoxO1 pathway. Kim, Ye Ra; Lee, Eun Kyeong; Kim, Dae Hyun; Kim, Kyung Mok; Lee, Bonggi; An, Hye Jin; Park, June Whoun; Moon, Kyoung Mi; Park, Min Hi; Chung, Ki Wung; Chung, Hae Young; Moon, Hyung Ryong Experimental Gerontology (2017), 92, 87-95.

163. Synthesis of benzo[b][1,4]oxazine-3(4H)-thione derivatives and their anti-tyrosinase activity. Kim, Do Hyun; Chun, Pusoon; Chung, Hae Young; Moon, Hyung Ryong; Yakhak Hoechi (2017), 61(1), 6-11.

162. Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. Kim Seong Min; Lee Bonggi; An Hye Jin; Kim Dae Hyun; Park Kyung Chul; Noh Sang-Gyun; Chung Ki Wung; Lee Eun Kyeong; Kim Kyung Mok; Kim Do Hyun; Chung Hae Young; ; Moon, Hyung Ryong Oncotarget (2017) In press.

161. Design, synthesis, and antimelanogenic effects of (2-substituted phenyl-1,3-dithiolan-4-yl)methanol derivatives. Kim Do Hyun; Kim Su Jeong; Ullah Sultan; Yun Hwi Young; Moon Hyung Ryong; Chun Pusoon; Drug design, development and therapy (2017), 11, 827-836.

160. Physiological characterization of a novel PPAR pan agonist, 2-(4-(5,6-methylenedioxybenzo[d]thiazol-2-yl)-2-methylphenoxy)-2-methylpropanoic acid (MHY2013)An Hye Jin; Lee Bonggi; Kim Dae Hyun; Lee Eun Kyeong; Chung Ki Wung; Park Min Hi; Jeong Hyoung Oh; Kim Sung Min; Moon Kyoung Mi; Kim Ye Ra; Moon, Hyung Ryong Oncotarget (2017), 8(10), 16912-16924.

159. Anticancer Effects of a New SIRT Inhibitor, MHY2256, against Human Breast Cancer MCF-7 Cells via Regulation of MDM2-p53 BindingPark Eun Young; Woo Youngwoo; Kim Seong Jin; Kim Do Hyun; Lee Eui Kyung; Lee Jaewon; Jung Jee H; Moon Hyung Ryong; De Umasankar; Kim Kyeong Seok; International journal of biological sciences (2016), 12(12), 1555-1567.

158. Increased therapeutic efficacy of a newly synthesized tyrosinase inhibitor by solid lipid nanoparticles in the topical treatment of hyperpigmentationAl-Amin Md; Cao Jiafu; Naeem Muhammad; Banna Hasanul; Kim Min-Soo; Jung Yunjin; Chung Hae Young; Moon Hyung Ryong; Yoo Jin-Wook Drug design, development and therapy (2016), 10, 3947-3957.

157. 4-(6,7-Dihydro-5H-indeno[5,6-d] thiazol-2-yl)benzene-1,3-diol prevents UV-induced melanogenesis and wrinkle formation in HRM-2 hairless mice Park June Whan; Ha Young Mi; Kim Dae Hyun; Lee Bonggi; Lee Eun Kyeong; Chung Ki Wung; Moon Kyoung Mi; Kim Kyung Mok; Park Yun Jung; Kim Do Hyun; Moon, Hyung Ryong Journal of dermatological science (2016), 84(2), 213-216.

156. (Z)-5-(2,4-Dihydroxybenzylidene)thiazolidine-2,4-dione Prevents UVB-Induced Melanogenesis and Wrinkle Formation through Suppressing Oxidative Stress in HRM-2 Hairless Mice Lee Bonggi; Moon Kyoung Mi; Kim Seong Jin; Kim So Hee; An Hye Jin; Jeong Ji Won; Kim Ye Ra; Son Sujin; Kim Min Jo; Chung Ki Wung; Moon, Hyung Ryong Oxidative medicine and cellular longevity (2016), 2016, 2761463.

155. Tyrosinase inhibitors: a patent review (2011-2015) Ullah Sultan; Son Sujin; Yun Hwi Young; Kim Do Hyun; Moon Hyung Ryong; Chun Pusoon Expert opinion on therapeutic patents (2016), 26(3), 347-62.

154. Antimelanogenic activity of MHY384 via inhibition of NO-induced cGMP signalling Moon Kyoung Mi; Jeong Ji Won; Lee Bonggi; Kim Dae Hyun; Lee Eun Kyeong; An Hye Jin; Kim Min Jo; Choi Yeon Ja; Chung Hae Young; Kim Hye Rim; Moon, Hyung Ryong Experimental dermatology (2016), 25(8), 652-4.

153. Petatewalide B, a novel compound from Petasites japonicus with anti-allergic activity Choi Young-Whan; Lee Young-Geun; Lee Kyoung-Pil; Kim Jung-Min; Kang Saeromi; Park Soo-Jin; Lee Jung-Min; Moon Hyung Ryong; Jung Jee H; Im Dong-Soon Journal of ethnopharmacology (2016), 178, 17-24.

152. Effects of MHY908, a New Synthetic PPARα/γ Dual Agonist, on Inflammatory Responses and Insulin Resistance in Aged Rats Park Min Hi; Kim Dae Hyun; Kim Min Jo; Lee Eun Kyeong; An Hye Jin; Jeong Ji Won; Kim Hye Rim; Kim Seong Jin; Moon Hyung Ryong; Chung Hae Young; The journals of gerontology. Series A, Biological sciences and medical sciences (2016), 71(3), 300-9.

151. (E)-2-Cyano-3-(substituted phenyl)acrylamide analogs as potent inhibitors of tyrosinase: A linear β-phenyl-α,β-unsaturated carbonyl scaffold Son Sujin; Kim Haewon; Yun Hwi Young; Kim Do Hyun; Ullah Sultan; Kim Seong Jin; Kim Min-Soo; Yoo Jin-Wook; Kim Yeon-Jeong; Chun Pusoon; Moon, Hyung Ryong Bioorganic & medicinal chemistry (2015), 23(24), 7728-34.

150. Dimeric Octaketide Spiroketals from the Jellyfish-Derived Fungus Paecilomyces variotii J08NF-1 Wang Haibo; Moon Hyung Ryong; Jung Jee H; Hong Jongki; Yin Jun; Liu Yonghong; Wei Xiaoyi; Oh Dong-Chan Journal of natural products (2015), 78(11), 2832-6.

149. Design, synthesis, and anti-melanogenic effects of (E)-2-benzoyl-3-(substituted phenyl)acrylonitriles Yun Hwi Young; Kim Do Hyun; Son Sujin; Ullah Sultan; Kim Seong Jin; Yoo Jin-Wook; Jung Yunjin; Moon Hyung Ryong; Kim Yeon-Jeong; Chun Pusoon Drug design, development and therapy (2015), 9, 4259-68.

148. Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process Ha Eun-Sol; Yoo Jin-Wook; Jung Yunjin; Moon Hyung Ryong; Kim Min-Soo; Kim Jeong-Soo; Baek In-Hwan Drug design, development and therapy (2015), 9, 4269-77.

147. A Novel Peroxisome Proliferator-activated Receptor (PPAR)γ Agonist 2-Hydroxyethyl 5-chloro-4,5-didehydrojasmonate Exerts Anti-Inflammatory Effects in Colitis Choo Jieun; Lee Yunna; Noh Tae Hwan; Kim Seong Jin; Son Sujin; Moon Hyung Ryong; Jung Jee H; Im Eunok; Yan Xin-Jia; Pothoulakis Charalabos Journal of biological chemistry (2015), 290(42), 25609-19.

146. Novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces cell cycle arrest and apoptosis via the downregulation of Akt in human lung cancer cells Lim Hyun Sook; Kang Yong Jung; Sung Bokyung; Kim Seon Hee; Kim Min Jeong; Kim Hye Rim; Kim Seong Jin; Moon Hyung Ryong; Chung Hae Young; Kim Nam Deuk; Oncology reports (2015), 34(5), 2431-8.

145. Evaluation of glycine-bearing celecoxib derivatives as a colon-specific mutual prodrug acting on nuclear factor-κB, an anti-inflammatory target Lee Sunyoung; Kim Wooseong; Nam Joon; Jeong Seongkeun; Yoo Jin-Wook; Kim Min-Soo; Moon Hyung Ryong; Jung Yunjin; Lee Yonghyun Drug design, development and therapy (2015), 9, 4227-37.

144. Colon-targeted delivery of budesonide using dual pH- and time-dependent polymeric nanoparticles for colitis therapy Naeem Muhammad; Choi Moonjeong; Cao Jiafu; Lee Yujeong; Lee Jaewon; Moon Hyung Ryong; Kim Min-Soo; Jung Yunjin; Yoo Jin-Wook; Ikram Muhammad; Drug design, development and therapy (2015), 9, 3789-99.

143. Enhanced therapeutic efficacy of budesonide in experimental colitis with enzyme/pH dual-sensitive polymeric nanoparticles Naeem Muhammad; Cao Jiafu; Choi Moonjeong; Kim Woo Seong; Moon Hyung Ryong; Lee Bok Luel; Kim Min-Soo; Jung Yunjin; Yoo Jin-Wook International journal of nanomedicine (2015), 10, 4565-80.

142. (2R/S,4R)-2-(2,4-Dihydroxyphenyl)thiazolidine-4-carboxylic acid prevents UV-induced wrinkle formation through inhibiting NF-κB-mediated inflammation Lee Bonggi; Moon Kyoung Mi; Han Yu Kyeong; Chung Ki Wung; Lee Eun Kyeong; An Hye Jin; Ullah Sultan; Son Sujin; Yun Hwi Young; Kim Dae Hyun; Moon, Hyung Ryong Journal of dermatological science (2015), 79(3), 313-6.

141. MHY218-induced apoptotic cell death is enhanced by the inhibition of autophagy in AGS human gastric cancer cells Choi Pyoung Rak; Kim Jae Hyun; Kim Sung Eun; Park Moo In; Park Seun Ja; Kang Yong Jung; Sung Bokyung; Moon Hyung Ryong; Chung Hae Young; Kim Nam Deuk; International journal of oncology (2015), 47(2), 563-72.

140. Inhibition of melanogenesis by 2-[4-(5-chlorobenzo[d]thiazol-2-yl)phenoxy]-2-methylpropanoic acid (MHY908) Park Min Hi; Kim Seong Jin; Jeong Hyoung Oh; Moon Kyoung Mi; Son Sujin; Kim Dae Hyun; Kim Hye Rim; Kim Min Jo; Yun Hwi Young; Chun Pusoon; Moon, Hyung Ryong Archives of pharmacal research (2015), 38(4), 505-11.

139. MHY-449, a novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, mediates oxidative stress-induced apoptosis in AGS human gastric cancer cells Kim, Seon Hee; Kang, Yong Jung; Sung, Bokyung; Kim, Dong Hwan; Lim, Hyun Sook; Kim, Hye Rim; Kim, Seong Jin; Yoon, Jeong-Hyun; Moon, Hyung Ryong; Chung, Hae Young; Oncology Reports (2015), 34(1), 288-294.

138.(Z)-2-(Benzo[d]thiazol-2-ylamino)-5-(substituted benzylidene)thiazol- 4(5H)-one derivatives as novel tyrosinase inhibitors Kang, Kyeong Ha; Lee, Bonggi; Son, Sujin; Yun, Hwi Young; Moon, Kyoung Mi; Jeong, Hyoung Oh; Kim, Dae Hyun; Lee, Eun Kyeong; Choi, Yeon Ja; Kim, Do Hyun; Moon, Hyung Ryong Biological & Pharmaceutical Bulletin (2015), 38(8), 1227-1233.

137.A new histone deacetylase inhibitor, MHY219, inhibits the migration of human prostate cancer cells via HDAC1 De, Umasankar; Kundu, Soma; Patra, Nabanita; Ahn, Mee Young; Ahn, Ji Hae; Son, Ji Yeon; Yoon, Jung Hyun; Moon, Hyung Ryoung; Lee, Byung Mu; Kim, Hyung Sik Biomolecules & Therapeutics (2015), 23(5), 434-441.

136. A new histone deacetylase inhibitor, MHY219, inhibits the migration of human prostate cancer cells via HDAC1 De, Umasankar; Kundu, Soma; Patra, Nabanita; Ahn, Mee Young; Ahn, Ji Hae; Son, Ji Yeon; Yoon, Jung Hyun; Moon, Hyung Ryoung; Lee, Byung Mu; Kim, Hyung Sik Biomolecules & Therapeutics (2015), 23(5), 434-441.

135. Highly efficient synthesis of conformationally fixed bicyclo[3.1.0]hexyl nucleosides with an ethenyl group at C3'-position as potential antiviral agents Kim, Seong Jin; Woo, Youngwoo; Park, Ah-Young; Kim, Hye Rim; Son, Sujin; Yun, Hwi Young; Chun, Pusoon; Moon, Hyung Ryong Bulletin of the Korean Chemical Society (2014), 35(9), 2649-2654.

134. Benzylidene-linked thiohydantoin derivatives as inhibitors of tyrosinase and melanogenesis: importance of the β-phenyl-α,β-unsaturated carbonyl functionality Kim, Hye Rim; Lee, Hye Jin; Choi, Yeon Ja; Park, Yun Jung; Woo, Youngwoo; Kim, Seong Jin; Park, Min Hi; Lee, Hee Won; Chun, Pusoon; Chung, Hae Young; Moon, Hyung Ryong MedChemComm (2014), 5(9), 1410-1417.

133. A novel oxiranylchromenone derivative, MHY336, induces apoptosis and cell cycle arrest via a p53- and p21-dependent pathway in HCT116 human colon cancer cells Lee, Sun Hwa; Kang, Yong Jung; Kim, Dong Hwan; Sung, Bokyung; Kang, Jin Ah; Chun, Pusoon; Yoon, Jeong-Hyun; Moon, Hyung Ryong; Kim, Hyung Sik; Chung, Hae Young; International Journal of Oncology (2014), 44(3), 943-949.

132. MHY-449, a novel dihydrobenzofuro[4,5-b][1,8] naphthyridin-6-one derivative, induces apoptotic cell death through modulation of Akt/FoxO1 and ERK signaling in PC3 human prostate cancer cells Lee, Sun Hwa; Kang, Yong Jung; Sung, Bokyung; Kim, Dong Hwan; Lim, Hyun Sook; Kim, Hye Rim; Kim, Seong Jin; Yoon, Jeong-Hyun; Moon, Hyung Ryong; Chung, Hae Young; International Journal of Oncology (2014), 44(3), 905-911.

131. A novel hydroxamic acid derivative, MHY218, induces apoptosis and cell cycle arrest through downregulation of NF-κB in HCT116 human colon cancer cells Kim, Mi Kyeong; Kang, Yong Jung; Kim, Dong Hwan; Hossain, Mohammad Akbar; Jang, Jung Yoon; Lee, Sun Hwa; Yoon, Jeong-Hyun; Chun, Pusoon; Moon, Hyung Ryong; Kim, Hyung Sik; International Journal of Oncology (2014), 44(1), 256-264.

130. A novel anthracene derivative, MHY412, induces apoptosis in doxorubicin-resistant MCF-7/Adr human breast cancer cells through cell cycle arrest and downregulation of P-glycoprotein expression De, Umasankar; Chun, Pusoon; Choi, Wahn Soo; Lee, Byung Mu; Kim, Nam Deuk; Moon, Hyung Ryong; Jung, Jee H.; Kim, Hyung Sik International Journal of Oncology (2014), 44(1), 167-176.

129. Identification of a novel anti-inflammatory compound, α-cubebenoate from Schisandra chinensis Kang, Saeromi; Lee, Kyoung-Pil; Park, Soo-Jin; Noh, Dae-Young; Kim, Jung-Min; Moon, Hyung Ryong; Lee, Young-Geun; Choi, Young-Whan; Im, Dong-Soon Journal of Ethnopharmacology (2014), 153(1), 242-249.

128. MHY884, a newly synthesized tyrosinase inhibitor, suppresses UVB-induced activation of NF-κB signaling pathway through the downregulation of oxidative stress Choi, Yeon Ja; Uehara, Yohei; Park, Ji Young; Kim, Seong Jin; Kim, So Ra; Lee, Hee Won; Moon, Hyung Ryong; Chung, Hae Young Bioorganic & Medicinal Chemistry Letters (2014), 24(5), 1344-1348.

127. Chinese prescription Kangen-karyu and Salviae Miltiorrhizae Radix improve age-related oxidative stress and inflammatory response through the PI3K/Akt or MAPK pathways Park Chan Hum; Kim Dae Hyun; Park Min Hi; Kim Mi Kyung; Kim Nam Deuk; Kim Cheol Min; Tanaka Takashi; Yokozawa Takako; Chung Hae Young; Moon Hyung Ryong American journal of Chinese medicine (2014), 42(4), 987-1005.

126. The novel PPAR α/γ dual agonist MHY 966 modulates UVB-induced skin inflammation by inhibiting NF-κB activity Park, Min Hi; Park, Ji Young; Lee, Hye Jin; Kim, Dae Hyun; Chung, Ki Wung; Park, Daeui; Jeong, Hyoung Oh; Kim, Hye Rim; Park, Chan Hum; Kim, So Ra; Moon, Hyung Ryong PLoS One (2013), 8(10), e76820.

125. De novo tyrosinase inhibitor: 4-(6,7-Dihydro-5H-indeno[5,6-d]thiazol-2-yl)benzene-1,3-diol (MHY1556) Park, June Whan; Ha, Young Mi; Moon, Kyoung-mi; Kim, So-ra; Jeong, Hyoung Oh; Park, Yun Jung; Lee, Hye Jin; Park, Ji Young; Song, Yu Min; Chun, Pusoon; Moon, Hyung Ryong Bioorganic & Medicinal Chemistry Letters (2013), 23(14), 4172-4176.

124. Characterization of a small molecule inhibitor of melanogenesis that inhibits tyrosinase activity and scavenges nitric oxide (NO) Chung, Ki Wung; Jeong, Hyoung Oh; Jang, Eun Ji; Choi, Yeon Ja; Kim, Dae Hyun; Kim, So Ra; Lee, Kyung Jin; Lee, Hye Jin; Chun, Pusoon; Byun, Youngjoo; Moon, Hyung Ryong Biochimica et Biophysica Acta, General Subjects (2013), 1830(10), 4752-4761.

123. Anti-melanogenic effect of (Z)-5-(2,4-dihydroxybenzylidene) thiazolidine-2,4-dione, a novel tyrosinase inhibitor Kim, So Hee; Ha, Young Mi; Moon, Kyoung Mi; Choi, Yeon Ja; Park, Yun Jung; Jeong, Hyoung Oh; Chung, Ki Wung; Lee, Hye Jin; Chun, Pusoon; Moon, Hyung Ryong Archives of Pharmacal Research (2013), 36(10), 1189-1197.

122. The inhibitory effect of a synthetic compound,(Z)5-(2,4-dihydroxybenzylidenethiazolidine-2,4-dione (MHY498), on nitric oxide-induced melanogenesis Kim, So Hee; Choi, Yeon Ja; Moon, Kyoung Mi; Lee, Hye Jin; Woo, Youngwoo; Chung, Ki Wung; Jung, Yuri; Kim, Sora; Chun, Pusoon; Byun, Youngjoo; Moon, Hyung Ryong Bioorganic & Medicinal Chemistry Letters (2013), 23(15), 4332-4335.

121. Synthesis of novel N-(2-hydroxyphenyl) aryl-sulfonamides as selective HDAC inhibitory and cytotoxic agents Kim, Jungsu; Chun, Pusoon; Moon, Hyung Ryong Bulletin of the Korean Chemical Society (2013), 34(5), 1487-1493.

120. Development of Akt-activated GSK3β inhibitory peptide Kim, Jin-Sik; Piao, Shunfu; Lee, Eunjin; Yoon, Bo-Young; Moon, Hyung Ryong; Lee, Jaewon; Jung, Yunjin; Ha, Nam-Chul Biochemical and Biophysical Research Communications (2013), 434(4), 735-739.

119. A novel histone deacetylase (HDAC) inhibitor MHY219 induces apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells Patra, Nabanita; De, Umasankar; Kim, Tae Hyung; Lee, Young Ju; Ahn, Mee Young; Kim, Nam Deuk; Yoon, Jung Hyun; Choi, Wahn Soo; Moon, Hyung Ryong; Lee, Byung Mu Biomedicine & Pharmacotherapy (2013), 67(5), 407-415.

118. Molecular docking studies of (1E,3E,5E)-1,6-bis(substituted phenyl)-hexa-1,3,5-triene and 1,4-bis(substituted trans-styryl)benzene analogs as novel tyrosinase inhibitors Ha, Young Mi; Lee, Hye Jin; Park, Daeui; Jeong, Hyoung Oh; Park, Ji Young; Park, Yun Jung; Lee, Kyung Jin; Lee, Ji Yeon; Moon, Hyung Ryong; Chung, Hae Young Biological & Pharmaceutical Bulletin (2013), 36(1), 55-65.

117. A novel synthesized tyrosinase inhibitor: (E)-2-((2,4-dihydroxyphenyl)diazenyl)phenyl 4-methylbenzenesulfonate as an azo-resveratrol analog Bae, Sung Jin; Ha, Young Mi; Kim, Jin-Ah; Park, Ji Young; Ha, Tae Kwun; Park, Daeui; Chun, Pusoon; Park, Nam Hee; Moon, Hyung Ryong; Chung, Hae Young Bioscience, Biotechnology, and Biochemistry (2013), 77(1), 65-72.

116. Potent anti-diabetic effects of MHY908, a newly synthesized PPAR α/γ dual agonist in db/db mice Park Min Hi; Park Ji Young; Lee Hye Jin; Kim Dae Hyun; Park Daeui; Jeong Hyoung Oh; Park Chan Hum; Chun Pusoon; Moon Hyung Ryong; Chung Hae Young PloS one (2013), 8(11), e78815.

115. Novel dihydrobenzofuro[04,5b]]1,8[naphthyridin-6-one derivative, MHY-449, induces apoptosis and cell cycle arrest in HCTll6 human colon cancer cells Hwang, Hye Jung; Kang, Yong Jung; Hossain, Mohammad Akbar; Kim, Dong Hwan; Jang, Jung Yoon; Lee, Sun Hwa; Yoon, Jeong-Hyun; Moon, Hyung Ryong; Kim, Hyung Sik; Chung, Hae Young; International Journal of Oncology (2012), 41(6), 2057-2064.c

114. Design, synthesis, and evaluation of (E)-N-substituted benzylidene-aniline derivatives as tyrosinase inhibitors Bae, Sung Jin; Ha, Young Mi; Park, Yun Jung; Park, Ji Young; Song, Yu Min; Ha, Tae Kwun; Chun, Pusoon; Moon, Hyung Ryong; Chung, Hae Young European Journal of Medicinal Chemistry (2012), 57, 383-390.

113. Synthesis and Preliminary In Vitro Biological Evaluation of 5-Chloro-2-(Substituted Phenyl)Benzo[d]Thiazole Derivatives Designed As Novel Antimelanogenesis Agents Ha, Young Mi; Uehara, Yohei; Park, Daeui; Jeong, Hyoung Oh; Park, Ji Young; Park, Yun Jung; Lee, Ji Yeon; Lee, Hye Jin; Song, Yu Min; Moon, Hyung Ryong; Applied Biochemistry and Biotechnology (2012), 168(6), 1416-1433.

112. Synthesis of novel azo-resveratrol, azo-oxyresveratrol and their derivatives as potent tyrosinase inhibitors Song, Yu Min; Ha, Young Mi; Kim, Jin-Ah; Chung, Ki Wung; Uehara, Yohei; Lee, Kyung Jin; Chun, Pusoon; Byun, Youngjoo; Chung, Hae Young; Moon, Hyung Ryong Bioorganic & Medicinal Chemistry Letters (2012), 22(24), 7451-7455.

111. A novel carbazole derivative, MHY407, sensitizes cancer cells to doxorubicin-, etoposide-, and radiation treatment via DNA damage Yoon, Sungpil; Kim, Ju-Hwa; Lee, Young Ju; Ahn, Mee Young; Choi, Gayoung; Kim, Won Ki; Yang, Zunhua; Lee, Hye Jin; Moon, Hyung Ryong; Kim, Hyung Sik European Journal of Pharmacology (2012), 697(1-3), 24-31.

110. Suppression of melanogenesis by a newly synthesized compound, MHY966 via the nitric oxide/protein kinase G signaling pathway in murine skin Choi, Yeon Ja; Uehara, Yohei; Park, Ji Young; Chung, Ki Wung; Ha, Young Mi; Kim, Ji Min; Song, Yu Min; Chun, Pusoon; Park, June Whan; Moon, Hyung Ryong Journal of Dermatological Science (2012), 68(3), 164-171.

109. A new synthetic HDAC inhibitor, MHY218, induces apoptosis or autophagy-related cell death in tamoxifen-resistant MCF-7 breast cancer cells Park, Ji Hye; Ahn, Mee Young; Kim, Tae Hyung; Yoon, Sungpill; Kang, Keon Wook; Lee, Jaewon; Moon, Hyung Ryong; Jung, Jee H.; Chung, Hae Young; Kim, Hyung Sik Investigational New Drugs (2012), 30(5), 1887-1898.

108. Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion Choi, Yeon Ja; Park, Yun Jung; Park, Ji Young; Jeong, Hyoung Oh; Kim, Dae Hyun; Ha, Young Mi; Kim, Ji Min; Song, Yu Min; Heo, Hyoung-Sam; Yu, Byung Pal; Moon, Hyung Ryong PLoS One (2012), 7(8), e43418.

107. Evaluation of in vitro and in vivo anti-melanogenic activity of a newly synthesized strong tyrosinase inhibitor (E)-3-(2,4-dihydroxybenzylidene)pyrrolidine-2,5-dione (3-DBP) Chung, Ki Wung; Park, Yun Jung; Choi, Yeon Ja; Park, Min Hi; Ha, Young Mi; Uehara, Yohei; Yoon, Jung Hyun; Chun, Pusoon; Moon, Hyung Ryong; Chung, Hae Young Biochimica et Biophysica Acta, General Subjects (2012), 1820(7), 962-969.

106. In vitro stability and in vivo anti-inflammatory efficacy of synthetic jasmonates Dang, Hung The; Lee, Yoon Mi; Kang, Gyeoung Jin; Yoo, Eun Sook; Hong, Jongki; Lee, Sun Mee; Lee, Sang Kook; Pyee, Yuna; Chung, Hwa-Jin; Moon, Hyung Ryong; Bioorganic & Medicinal Chemistry (2012), 20(13), 4109-4116.

105. Pulmonary administered palmitic-acid modified exendin-4 peptide prolongs hypoglycemia in type 2 diabetic db/db mice Lee, Juho; Lee, Changkyu; Kim, Tae Hyung; Chi, Sang-Cheol; Moon, Hyung Ryong; Oh, Kyung Taek; Lee, Eun Seong; Lee, Kang Choon; Youn, Yu Seok Regulatory Peptides (2012), 177(1-3), 68-72.

104. Characterization of a novel tyrosinase inhibitor, (2RS,4R)-2-(2,4-dihydroxyphenyl)thiazolidine-4-carboxylic acid (MHY384) Han, Yu Kyeong; Park, Yun Jung; Ha, Young Mi; Park, Daeui; Lee, Ji Yeon; Lee, Naree; Yoon, Jeong Hyun; Moon, Hyung Ryong; Chung, Hae Young Biochimica et Biophysica Acta, General Subjects (2012), 1820(4), 542-549.

103. Design and synthesis of 5-(substituted benzylidene)thiazolidine-2,4-dione derivatives as novel tyrosinase inhibitors Ha, Young Mi; Park, Yun Jung; Kim, Jin-Ah; Park, Daeui; Park, Ji Young; Lee, Hye Jin; Lee, Ji Yeon; Moon, Hyung Ryong; Chung, Hae Young European Journal of Medicinal Chemistry (2012), 49, 245-252.

102. Preparation and evaluation of palmitic acid-conjugated exendin-4 with delayed absorption and prolonged circulation for longer hypoglycemia Lee, Juho; Lee, Changkyu; Kim, Insoo; Moon, Hyung Ryong; Kim, Tae Hyung; Oh, Kyung Taek; Lee, Eun Seong; Lee, Kang Choon; Youn, Yu Seok International Journal of Pharmaceutics (Amsterdam, Netherlands) (2012), 424(1-2), 50-57.

101. Design, synthesis and biological evaluation of 2-(substituted phenyl)thiazolidine-4-carboxylic acid derivatives as novel tyrosinase inhibitors Ha, Young Mi; Park, Yun Jung; Lee, Ji Yeon; Park, Daeui; Choi, Yeon Ja; Lee, Eun Kyeong; Kim, Ji Min; Kim, Jin-Ah; Park, Ji Young; Lee, Hye Jin; Moon, Hyung Ryong Biochimie (2012), 94(2), 533-540.

100. Crystallization and preliminary X-ray crystallographic analysis of the β-N-acetylglucosaminidase CbsA from Thermotoga neapolitana Yoon, Bo-Young; Jiao, Li; Moon, Hyung Ryong; Cha, Jaeho; Ha, Nam-Chul Acta Crystallographica, Section F: Structural Biology and Crystallization Communications (2012), 68(1), 56-58.

99. Stereoselective synthesis and anti-HCV activity of conformationally restricted 2'-C-substituted carbanucleosides Choi, Won Jun; Ko, Yun Jung; Chandra, Girish; Lee, Hyuk Woo; Kim, Hea Ok; Koh, Hyo Jung; Moon, Hyung Ryong; Jung, Young Hoon; Jeong, Lak Shin Tetrahedron (2012), 68(4), 1253-1261.

98. Design, synthesis and anticancer activity of novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivatives Kang, Jin-Ah; Yang, Zunhua; Lee, Ji Yeon; De, Umasankal; Kim, Tae Hyung; Park, Ji Young; Lee, Hye Jin; Park, Yun Jung; Chun, Pusoon; Kim, Hyung Sik; Moon, Hyung Ryong Bioorganic & Medicinal Chemistry Letters (2011), 21(19), 5730-5734.

97. Synthesis and importance of bulky aromatic cap of novel SAHA analogs for HDAC inhibition and anticancer activity Chun, Pusoon; Kim, Won Hee; Kim, Jungsu; Kang, Jin-Ah; Lee, Hye Jin; Park, Ji Young; Ahn, Mee Young; Kim, Hyung Sik; Moon, Hyung Ryong Bulletin of the Korean Chemical Society (2011), 32(6), 1891-1896.

96. Synthesis of enantiomerically pure D- and L-bicyclo[3.1.0]hexenyl carbanucleosides and their antiviral evaluation Park, Ah-Young; Kim, Won Hee; Kang, Jin-Ah; Lee, Hye Jin; Lee, Chong-Kyo; Moon, Hyung Ryong Bioorganic & Medicinal Chemistry (2011), 19(13), 3945-3955.

95. Synthesis and biological activity of hydroxybenzylidene pyrrolidine-2,5-dione derivatives as new potent inhibitors of tyrosinase Ha, Young Mi; Kim, Jin-Ah; Park, Yun Jung; Park, Daeui; Choi, Yeon Ja; Kim, Ji Min; Chung, Ki Wung; Han, Yu Kyeong; Park, Ji Young; Lee, Ji Yeon; Moon, Hyung Ryong MedChemComm (2011), 2(6), 542-549.

94. Crystallization and preliminary x-ray crystallographic analysis of Salmonella typhimurium CueP Yun, Bo Young; Piao, Shunfu; Kim, Yeon Gil; Moon, Hyung Ryong; Choi, Eun Joo; Kim, Young Ok; Nam, Bo Hye; Lee, Sang Jun; Ha, Nam Chul Acta Crystallographica, Section F: Structural Biology and Crystallization Communications (2011), 67(6), 675-677.

93. Analogs of 5-(substituted benzylidene)hydantoin as inhibitors of tyrosinase and melanin formation Ha, Young Mi; Kim, Jin-Ah; Park, Yun Jung; Park, Daeui; Kim, Ji Min; Chung, Ki Wung; Lee, Eun Kyeong; Park, Ji Young; Lee, Ji Yeon; Lee, Hye Jin; Moon, Hyung Ryong Biochimica et Biophysica Acta, General Subjects (2011), 1810(6), 612-619.

92. Synthesis and biological activity of hydroxy substituted phenyl-benzo[d]thiazole analogues for antityrosinase activity in B16 cells Ha, Young Mi; Park, Ji Young; Park, Yun Jung; Park, Daeui; Choi, Yeon Ja; Kim, Ji Min; Lee, Eun Kyeong; Han, Yu Kyeong; Kim, Jin-Ah; Lee, Ji Yeon; Moon, Hyung Ryong Bioorganic & Medicinal Chemistry Letters (2011), 21(8), 2445-2449.

91. A novel epoxypropoxy flavonoid derivative and topoisomerase II inhibitor, MHY336, induces apoptosis in prostate cancer cells Patra, Nabanita; De, Umasankar; Kang, Jin-Ah; Kim, Ji Mim; Ahn, Mee Young; Lee, Jaewon; Jung, Jee H.; Chung, Hae Young; Moon, Hyung Ryong; Kim, Hyung Sik European Journal of Pharmacology (2011), 658(2-3), 98-107.

90. Anticancer effects of the MHY218 novel hydroxamic acid-derived histone deacetylase inhibitor in human ovarian cancer cells Jeon, Heui Sook; Ahn, Mee Young; Park, Ji Hye; Kim, Tae Hyung; Chun, Pusoon; Kim, Won Hee; Kim, Jungsu; Moon, Hyung Ryong; Jung, Jee H.; Kim, Hyung Sik International Journal of Oncology (2010), 37(2), 419-428.

89. Using conformationally locked nucleosides to calibrate the anomeric effect: implications for glycosyl bond stability Moon, Hyung Ryong; Siddiqui, Maqbool A.; Sun, Guangyu; Filippov, Igor V.; Landsman, Nicholas A.; Lee, Yi-Chien; Adams, Kristie M.; Barchi, Joseph J., Jr.; Deschamps, Jeffrey R.; Nicklaus, Marc C Tetrahedron (2010), 66(34), 6707-6717.

88. First synthesis of 2'-oxabicyclo[3.1.0]hexyl nucleosides with a north conformation Kim, Won Hee; Park, Ah-Young; Kang, Jin-Ah; Kim, Jungsu; Kim, Jin-Ah; Lee, Hyung-Rock; Chun, Pusoon; Choi, Jungwon; Lee, Chong-Kyo; Jeong, Lak Shin; Moon, Hyung Ryong Tetrahedron (2010), 66(9), 1706-1715.

87. Highly concise synthesis of 3'-"up"-ethynyl-5'-methylbicyclo-[3.1.0]hexyl purine and pyrimidine nucleoside derivatives using rhodium(II) carbenoid cycloaddition and highly diastereoselective Grignard reaction Yang, Zunhua; Kim, Kyung Ran; Park, Ah-Young; Lee, Hyung-Rock; Kang, Jin-Ah; Kim, Won Hee; Chun, Pusoon; Gong, Ping; Lee, Boeun; Jeong, Lak Shin; Moon, Hyung Ryong Chinese Journal of Chemistry (2009), 27(12), 2405-2412.

86. Design and synthesis of N6-substituted-4'-thioadenosine-5'-uronamides as potent and selective human A3 adenosine receptor agonists Choi, Won Jun; Lee, Hyuk Woo; Kim, Hea Ok; Chinn, Moshe; Gao, Zhan-Guo; Patel, Amit; Jacobson, Kenneth A.; Moon, Hyung Ryong; Jung, Young Hoon; Jeong, Lak Shin Bioorganic & Medicinal Chemistry (2009), 17(23), 8003-8011.

85. Efficient and practical synthesis of L-hamamelose Kim, Won Hee; Kang, Jin-Ah; Lee, Hyung-Rock; Park, Ah-Young; Chun, Pusoon; Lee, Boeun; Kim, Jungsu; Kim, Jin-Ah; Jeong, Lak Shin; Moon, Hyung Ryong Carbohydrate Research (2009), 344(17), 2317-2321.

84. Synthesis of neplanocin A analog with 2'-"up"-C-Methyl substituent as potential anti-HCV agent Lee, Hyung-Rock; Kang, Jin-Ah; Park, Ah-Young; Kim, Won Hee; Chun, Pusoon; Kim, Jungsu; Kim, Jin-Ah; Lee, Boeun; Jeong, Lak Shin; Moon, Hyung Ryong Bulletin of the Korean Chemical Society (2009), 30(9), 2043-2050.

83. Design, synthesis, antitumor activity and mode of action of novel oxiranyl and thiiranyl phenol derivatives Yang, Zunhua; Kang, Jin-Ah; Kim, Won Hee; Park, Ah-Young; Kim, Hyung Sik; Kim, Jungsu; Kim, Jin-Ah; Gong, Ping; Jeong, Lak Shin; Moon, Hyung Ryong Bulletin of the Korean Chemical Society (2009), 30(7), 1463-1469.

82. Design and synthesis of 5''-iodoneplanocin A and its analogues as potential S-adenosylhomocysteine hydrolase inhibitor Park, Ah-Young; Kim, Kyung Ran; Lee, Hyung-Rock; Kang, Jin-Ah; Kim, Won Hee; Chun, Pusoon; Ahmad, Pervez; Jeong, Lak Shin; Moon, Hyung Ryong Bulletin of the Korean Chemical Society (2008), 29(12), 2487-2490.

81. Synthesis of methyl-substituted bicyclic carbanucleoside analogs as potential antiherpetic agents Kim, Kyung Ran; Park, Ah-Young; Lee, Hyung-Rock; Kang, Jin-Ah; Kim, Won Hee; Chun, Pusoon; Bae, Jang Ho; Jeong, Lak Shin; Moon, Hyung Ryong Bulletin of the Korean Chemical Society (2008), 29(10), 1977-1982.

80. Structure-Activity Relationships of Truncated D- and L-4'-Thioadenosine Derivatives as Species-Independent A3 Adenosine Receptor Antagonists Jeong, Lak Shin; Pal, Shantanu; Choe, Seung Ah; Choi, Won Jun; Jacobson, Kenneth A.; Gao, Zhan-Guo; Klutz, Athena M.; Hou, Xiyan; Kim, Hea Ok; Lee, Hyuk Woo; Moon, Hyung Ryong Journal of Medicinal Chemistry (2008), 51(20), 6609-6613.

79. Synthesis and biological evaluation of 5''-iodoneplanocin A and its analogs Park, Ah-Young; Kim, Kyung Ran; Lee, Hyung-Rock; Kang, Jin-Ah; Kim, Won Hee; Jeong, Lak Shin; Moon, Hyung Ryong Nucleic Acids Symposium Series (2008), 52(1), 653-654.

78. Synthesis and antiviral evaluation of conformationally fixed bicyclohexanyl nucleosides with ethenyl group at C3'-position Kim, Won Hee; Kim, Kyung Ran; Park, Ah-Young; Lee, Hyung-Rock; Kang, Jin-Ah; Bae, Jang Ho; Jeong, Lak Shin; Moon, Hyung Ryong Nucleic Acids Symposium Series (2008), 52(1), 621-622.

77. Synthesis of novel cyclopropyl nucleoside analogs as potential antiherpetic agent Kang, Jin-Ah; Park, Ah-Young; Lee, Hyung-Rock; Kim, Won Hee; Chun, Pusoon; Jeong, Lak Shin; Moon, Hyung Ryong Nucleic Acids Symposium Series (2008), 52(1), 613-614.

76. Synthesis of pyrimidine analog of fluoroneplanocin A as potential anti-HCV agent Lee, Hyung-Rock; Kim, Won Hee; Park, Ah-Young; Kang, Jin-Ah; Chun, Pusoon; Bae, Jang Ho; Jeong, Lak Shin; Moon, Hyung Ryong Nucleic Acids Symposium Series (2008), 52(1), 607-608.

75. Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor Lee, Ga Eun; Joshi, Bhalchandra V.; Chen, Wangzhong; Jeong, Lak Shin; Moon, Hyung Ryong; Jacobson, Kenneth A.; Kim, Yong-Chul Bioorganic & Medicinal Chemistry Letters (2008), 18(2), 571-575.

74. Design, Enantiopure Synthesis, and Biological Evaluation of Novel ISO-D-2',3'-Dideoxy-3'-Fluorothianucleoside Derivatives as a bioisostere of Lamivudine Kim, Kyung Ran; Park, Ah-Young; Moon, Hyung Ryong; Chun, Moon Woo; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2007), 26(8-9), 911-915.

73. Asymmetric Synthesis of Cyclopropyl-fused 2'-C-Methylcarbanucleosides as Potential Anti-HCV Agents Jeong, Lak Shin; Lee, Jeong A.; Kim, Hea Ok; Tosh, Dilip K.; Moon, Hyung Ryong; Lee, Seung-Jin; Lee, Kang Man; Sheen, Yhun Y.; Chun, Moon Woo Nucleosides, Nucleotides & Nucleic Acids (2007), 26(8-9), 1021-1024.

72. Stereoselective Synthesis of 1'-Functionalized-4'-Thionucleosides Jeong, Lak Shin; Gunaga, Prashantha; Kim, Hea Ok; Tosh, Dilip K.; Lee, Hyuk Woo; Choe, Seung Ah; Moon, Hyung Ryong; Gao, Zhan-Guo; Jacobson, Kenneth A.; Chun, Moon Woo Nucleosides, Nucleotides & Nucleic Acids (2007), 26(8-9), 1011-1014.

71. Asymmetric Synthesis of Novel Pseudo-D-Vinylcyclopropyl Nucleosides Bearing Quaternary Carbon as Potential Anti-Herpesvirus Agent Park, Ah-Young; Moon, Hyung Ryong; Kim, Kyung Ran; Chun, Moon Woo; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2007), 26(8-9), 1001-1004.

70. Synthesis of Enantiopure Pseudo-L-Vinylcyclopropyl Nucleosides Bearing Quaternary Carbon as Potential Anti-Herpesvirus Agent Moon, Hyung Ryong; Park, Ah-Young; Kim, Kyung Ran; Chun, Moon Woo; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2007), 26(8-9), 975-978.

69. Asymmetric Synthesis of Apio Fluoroneplanocin A Analogs as Potential AdoHcy Hydrolase Inhibitor Park, Ah-Young; Moon, Hyung Ryong; Kim, Kyung Ran; Kang, Jin-Ah; Chun, Moon Woo; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2007), 26(8-9), 943-947.

68. Synthesis And Anti-HCV Activity Of 2'-β-Hydroxymethylated Nucleosides Jeong, Lak Shin; Yoo, Byul Nae; Kim, Hea Ok; Lee, Kang Man; Moon, Hyung Ryong Nucleosides, Nucleotides & Nucleic Acids (2007), 26(6-7), 725-728.

67. Asymmetric Synthesis of Novel Apio Carbocyclic Nucleoside Analogues as Potential Antiviral and Antitumor Agent Jeong, Lak Shin; Lee, Jeong A.; Moon, Hyung Ryong; Kim, Hea Ok; Lee, Kang Man; Lee, Hyun Joo; Chun, Moon Woo Nucleosides, Nucleotides & Nucleic Acids (2007), 26(6-7), 721-724.

66. Synthesis of N6-Substituted 3'-Ureidoadenosine Derivatives as Highly Potent Agonists at the Mutant A3 Adenosine Receptor Jeong, Lak Shin; Choe, Seung Ah; Kim, Ae Yil; Kim, Hea Ok; Gao, Zhan-Guo; Jacobson, Kenneth A.; Chun, Moon Woo; Moon, Hyung Ryong Nucleosides, Nucleotides & Nucleic Acids (2007), 26(6-7), 717-719.

65. Synthesis and Antitumor Activity of Fluorocyclopentenyl-Pyrimidines Jeong, Lak Shin; Zhao, Long Xuan; Choi, Won Jun; Pal, Shantanu; Park, Yeon Hee; Lee, Sang Kook; Chun, Moon Woo; Lee, Young B.; Ahn, Chang Ho; Moon, Hyung Ryong Nucleosides, Nucleotides & Nucleic Acids (2007), 26(6-7), 713-716.

64. Stereoselective Synthesis Of Homo-Apioneplanocin A As Potential Inhibitor Of S-Adenosylhomocysteine Hydrolase Chun, Moon Woo; Lee, Hyuk Woo; Kim, Jin-Hee; Kim, Hea Ok; Lee, Kang Man; Pal, Shantanu; Moon, Hyung Ryong; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2007), 26(6-7), 729-732.

63. Design, Synthesis, and Antitumor Activity of 4'-Thionucleosides as Potent and Selective Agonists at the Human A3 Adenosine Receptor Jeong, Lak Shin; Lee, Hyuk Woo; Kim, Hea Ok; Jung, Ji Young; Gunaga, Prashantha; Lee, Sang Kook; Lee, Eun-Jin; Chun, Moon Woo; Gao, Zhan-Guo; Jacobson, Kenneth A.; Moon, Hyung Ryong Nucleosides, Nucleotides & Nucleic Acids (2007), 26(10-12), 1565-1568.

62. Asymmetric Synthesis and Biological Activity of L-Bicyclocarba-d4T Moon, Hyung Ryong; Park, Ah-Young; Kim, Kyung Ran; Chun, Moon Woo; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2007), 26(10-12), 1653-1657.

61. Design, synthesis, and molecular modeling studies of 5'-deoxy-5'-ureidoadenosine: 5'-ureido group as multiple hydrogen bonding donor in the active site of S-adenosylhomocysteine hydrolase Wang, Ting; Lee, Hyun Joo; Tosh, Dilip K.; Kim, Hea Ok; Pal, Shantanu; Choi, Sun; Lee, Yoonji; Moon, Hyung Ryong; Zhao, Long Xuan; Lee, Kang Man; Bioorganic & Medicinal Chemistry Letters (2007), 17(16), 4456-4459.

60. Discovery of a New Nucleoside Template for Human A3 Adenosine Receptor Ligands: D-4'-Thioadenosine Derivatives without 4'-Hydroxymethyl Group as Highly Potent and Selective Antagonists Jeong, Lak Shin; Choe, Seung Ah; Gunaga, Prashantha; Kim, Hea Ok; Lee, Hyuk Woo; Lee, Sang Kook; Tosh, Dilip K.; Patel, Amit; Palaniappan, Krishnan K.; Gao, Zhan-Guo; Moon, Hyung Ryong Journal of Medicinal Chemistry (2007), 50(14), 3159-3162.

59. Design, synthesis, and biological evaluation of novel iso-D-2',3'-dideoxy-3'-fluorothianucleoside derivatives Kim, Kyung Ran; Moon, Hyung Ryong; Park, Ah-Young; Chun, Moon Woo; Jeong, Lak Shin Bioorganic & Medicinal Chemistry (2007), 15(1), 227-234.

58. Synthesis of novel L-N-MCd4T as a potent anti-HIV agent Park, Ah-Young; Moon, Hyung Ryong; Kim, Kyung Ran; Chun, Moon Woo; Jeong, Lak Shin Organic & Biomolecular Chemistry (2006), 4(22), 4065-4067.

57. Stereoselective Synthesis of 2'-C-Methyl-cyclopropyl-Fused Carbanucleosides as Potential Anti-HCV Agents Lee, Jeong A.; Kim, Hea Ok; Tosh, Dilip K.; Moon, Hyung Ryong; Kim, Sanghee; Jeong, Lak Shin Organic Letters (2006), 8(22), 5081-5083.

56. Synthesis of 2-C-hydroxymethylribofuranosylpurines as potent anti-hepatitis C virus (HCV) agents Yoo, Byul Nae; Kim, Hea Ok; Moon, Hyung Ryong; Seol, Su Kyung; Jang, Sung Key; Lee, Kang Man; Jeong, Lak Shin Bioorganic & Medicinal Chemistry Letters (2006), 16(16), 4190-4194.

55. Asymmetric synthesis of homo-apioneplanocin A from D-ribose Kim, Jin-Hee; Kim, Hea Ok; Lee, Kang Man; Chun, Moon Woo; Moon, Hyung Ryong; Jeong, Lak Shin Tetrahedron (2006), 62(26), 6339-6342.

54. Design, synthesis, and biological activity of N6-substituted-4'-thioadenosines at the human A3 adenosine receptor Jeong, Lak Shin; Lee, Hyuk Woo; Kim, Hea Ok; Jung, Ji Young; Gao, Zhan-Guo; Duong, Heng T.; Rao, Srikar; Jacobson, Kenneth A.; Shin, Dae Hong; Lee, Jeong A.; Moon, Hyung Ryong Bioorganic & Medicinal Chemistry (2006), 14(14), 4718-4730.

53. Structure-Activity Relationships of 2-Chloro-N6-substituted-4'-thioadenosine-5'-uronamides as Highly Potent and Selective Agonists at the Human A3 Adenosine Receptor Jeong, Lak Shin; Lee, Hyuk Woo; Jacobson, Kenneth A.; Kim, Hea Ok; Shin, Dae Hong; Lee, Jeong A.; Gao, Zhan-Guo; Lu, Changrui; Duong, Heng T.; Gunaga, Prashantha; Moon, Hyung Ryong Journal of Medicinal Chemistry (2006), 49(1), 273-281.

52. Stereoselective synthesis of conformationally rigid apio carbanucleosides as potential antiviral agents Moon, Hyung Ryong; Kim, Kyung Ran; Kim, Bum Tae; Hwang, Ki Jun; Chun, Moon Woo; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2005), 24(5-7), 709-711.

51. Structure-activity relationship of 5'-substituted fluoro-neplanocin A analogues as potent inhibitors of S-adenosylhomocysteine hydrolase Moon, Hyung Ryong; Lee, Kang Man; Lee, Hyun Joo; Lee, Sang Kook; Park, Seung Bin; Chun, Moon Woo; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2005), 24(5-7), 707-708.

50. Stereoselective synthesis of 3-hydroxymethyl-D-cyclopentenone, the versatile intermediate for the synthesis of carbocyclic nucleosides Choi, Won Jun; Moon, Hyung Ryong; Kim, Hea Ok; Ko, Young Mi; Kim, Hye Jin; Lee, Jeong A.; Lee, Kang Man; Yun, Mi Kyung; Shin, Dae Hong; Chun, Moon Woo; Nucleosides, Nucleotides & Nucleic Acids (2005), 24(5-7), 611-613.

49. A highly efficient synthesis of unnatural L-sugars from D-ribose Yun, Mikyung; Moon, Hyung Ryong; Kim, Hea Ok; Choi, Won Jun; Kim, Yong-Chul; Park, Chul-Seung; Jeong, Lak Shin Tetrahedron Letters (2005), 46(35), 5903-5905.

48. A New Synthetic Route to (North)-Methano-carba Nucleosides Designed as A3 Adenosine Receptor Agonists Joshi, Bhalchandra V.; Moon, Hyung Ryong; Fettinger, James C.; Marquez, Victor E.; Jacobson, Kenneth A. Journal of Organic Chemistry (2005), 70(2), 439-447.

47. Synthesis of Novel Apio Carbocyclic Nucleoside Analogues as Selective A3 Adenosine Receptor Agonists Lee, Jeong A.; Moon, Hyung Ryong; Kim, Hea Ok; Kim, Kyung Ran; Lee, Kang Man; Kim, Bum Tae; Hwang, Ki Jun; Chun, Moon Woo; Jacobson, Kenneth A.; Jeong, Lak Shin Journal of Organic Chemistry (2005), 70(13), 5006-5013.

46. A New Synthetic Route to (North)-Methano-carba Nucleosides Designed as A3 Adenosine Receptor Agonists Joshi, Bhalchandra V.; Moon, Hyung Ryong; Fettinger, James C.; Marquez, Victor E.; Jacobson, Kenneth A. Journal of Organic Chemistry (2005), 70(2), 439-447.

45. Synthesis of 5'-substituted fluoro-neplanocin A analogs: importance of a hydrogen bonding donor at 5'-position for the inhibitory activity of S-adenosylhomocysteine hydrolase Moon, Hyung Ryong; Lee, Hyun Joo; Kim, Kyung Ran; Lee, Kang Man; Lee, Sang Kook; Kim, Hea Ok; Chun, Moon Woo; Jeong, Lak Shin Bioorganic & Medicinal Chemistry Letters (2004), 14(22), 5641-5644.

44. Recent advances in 4'-thionucleosides as potential antiviral and antitumor agents Gunaga, Prashantha; Moon, Hyung Ryong; Choi, Won Jun; Shin, Dae Hong; Park, Jae Gyu; Jeong, Lak Shin Current Medicinal Chemistry (2004), 11(19), 2585-2637.

43. Preparative synthesis of the key intermediate, (4R,5R)-3-Benzyloxymethyl-4,5-isopropylidenedioxycyclopent-2-enone for carbocyclic nucleosides Moon, Hyung Ryong; Choi, Won Jun; Kim, Hea Ok; Jeong, Lak Shin Chemistry Letters (2004), 33(5), 506-507.

42. Synthesis of fluorinated cyclopentenyladenine as potent inhibitor of S-adenosylhomocysteine hydrolase Kim, Hea Ok; Yoo, Su Jeong; Ahn, Hee Sung; Choi, Won Jun; Moon, Hyung Ryong; Lee, Kang Man; Chun, Moon Woo; Jeong, Lak Shin Bioorganic & Medicinal Chemistry Letters (2004), 14(9), 2091-2093.

41. Synthesis and biological evaluation of novel tert-azido or tert-amino substituted penciclovir analogs Kim, Hea Ok; Baek, Hye Won; Moon, Hyung Ryong; Kim, Dae-Kee; Chun, Moon Woo; Jeong, Lak Shin Organic & Biomolecular Chemistry (2004), 2(8), 1164-1168.

40. Preparative and Stereoselective Synthesis of the Versatile Intermediate for Carbocyclic Nucleosides: Effects of the Bulky Protecting Groups to Enforce Facial Selectivity Choi, Won Jun; Moon, Hyung Ryong; Kim, Hea Ok; Yoo, Byul Nae; Lee, Jeong A.; Shin, Dae Hong; Jeong, Lak Shin Journal of Organic Chemistry (2004), 69(7), 2634-2636.

39. Synthesis of D- and L-apio nucleoside analogues with 2'-hydroxyl group as potential anti-HIV agents Jin, Dong Zhe; Kwon, Sung Hee; Moon, Hyung Ryong; Gunaga, Prashantha; Kim, Hea Ok; Kim, Dae-Kee; Chun, Moon Woo; Jeong, Lak Shin Bioorganic & Medicinal Chemistry (2004), 12(5), 1101-1109.

38. Structural determinants of efficacy at A3 adenosine receptors: modification of the ribose moiety Gao, Zhan-Guo; Jeong, Lak Shin; Moon, Hyung Ryong; Kim, Hea Ok; Choi, Won Jun; Shin, Dae Hong; Elhalem, Eleonora; Comin, Maria J.; Melman, Neli; Mamedova, Liaman Biochemical Pharmacology (2004), 67(5), 893-901.

37. Design, Synthesis, and In Vitro Evaluation of APIO Analogue of Neplanocin A Moon, Hyung Ryong; Kwon, Sung Hee; Lee, Jeong Ah; Yoo, Byul Nae; Kim, Hea Ok; Chun, Moon Woo; Kim, Hee-Doo; Kim, Joong Hyup; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2003), 22(5-8), 1475-1477.

36. Design and Synthesis of A3 Adenosine Receptor Ligands, 3'-Fluoro Analogues of Cl-IB-MECA Kim, Hea Ok; Lim, Moo Hong; Park, Jae Gyu; Moon, Hyung Ryong; Jacobson, Kenneth A.; Kim, Hee-Doo; Chun, Moon Woo; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2003), 22(5-8), 923-925.

35. Design and Synthesis of A3 Adenosine Receptor Ligands, 2'-Fluoro Analogues of Cl-IB-MECA Kim, Hea Ok; Park, Jae Gyu; Moon, Hyung Ryong; Gunaga, Prashantha; Lim, Moo Hong; Chun, Moon Woo; Jacobson, Kenneth A.; Kim, Hee-Doo; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2003), 22(5-8), 927-930.

34. Synthesis of Halogenated 9-(Dihydroxycyclopent-4'-enyl) Adenines and Their Inhibitory Activities Against S-Adenosylhomocysteine Hydrolase Jeong, Lak Shin; Park, Jae Gyu; Choi, Won Jun; Moon, Hyung Ryong; Lee, Kang Man; Kim, Hea Ok; Kim, Hee-Doo; Chun, Moon Woo; Park, Hea-Young; Kim, Kilhyoun Nucleosides, Nucleotides & Nucleic Acids (2003), 22(5-8), 919-921.

33. Synthesis of 5-Azacytidine Nucleosides with Rigid Sugar Moiety as Potential Antitumor Agents Chun, Moon Woo; Kim, Myong Jung; Kim, Hea Ok; Kim, Hee-Doo; Kim, Joong Hyup; Moon, Hyung Ryong; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2003), 22(5-8), 915-917.

32. Synthesis and Biological Evaluation of Pyrimidine Nucleosides Fused with 3',4'-Tetrahydrofuran Ring Chun, Moon Woo; Kim, Myong Jung; Kim, Hea Ok; Moon, Hyung Ryong; Kim, Hee-Doo; Kim, Joong Hyup; Jeong, Lak Shin Nucleosides, Nucleotides & Nucleic Acids (2003), 22(5-8), 719-721.

31. Synthesis and Biological Evaluation of Halo-neplanocin A as Novel Mechanism-Based Inhibitors of S-Adenosylhomocysteine Hydrolase Jeong, Lak Shin; Moon, Hyung Ryong; Park, Jae Gyu; Shin, Dae Hong; Choi, Won Jun; Lee, Kang Man; Kim, Hea Ok; Chun, Moon Woo; Kim, Hee-Doo; Kim, Joong Hyup Nucleosides, Nucleotides & Nucleic Acids (2003), 22(5-8), 589-592.

30. Recent Advances in the Synthesis of Conformationally Locked Nucleosides and Their Success in Probing the Critical Question of Conformational Preferences by Their Biological Targets Choi, Yongseok; Moon, Hyung R.; Yoshimura, Yuichi; Marquez, Victor E. Nucleosides, Nucleotides & Nucleic Acids (2003), 22(5-8), 547-557.

29. N6-Substituted D-4'-Thioadenosine-5'-methyluronamides: Potent and Selective Agonists at the Human A3 Adenosine Receptor Jeong, Lak Shin; Jin, Dong Zhe; Kim, Hea Ok; Shin, Dae Hong; Moon, Hyung Ryong; Gunaga, Prashantha; Chun, Moon Woo; Kim, Yong-Chul; Melman, Neli; Gao, Zhan-Guo; Journal of Medicinal Chemistry (2003), 46(18), 3775-3777.

28. Design, synthesis and binding affinity of 3'-fluoro analogues of Cl-IB-MECA as adenosine A3 receptor ligands Lim, Moo Hong; Kim, Hea Ok; Moon, Hyung Ryong; Lee, Seung Jin; Chun, Moon Woo; Gao, Zhan-Guo; Melman, Neli; Jacobson, Kenneth A.; Kim, Joong Hyup; Jeong, Lak Shin Bioorganic & Medicinal Chemistry Letters (2003), 13(5), 817-820.

27. Design, Synthesis, and Biological Evaluation of Fluoroneplanocin A as the Novel Mechanism-Based Inhibitor of S-Adenosylhomocysteine Hydrolase Jeong, Lak Shin; Yoo, Su Jeong; Lee, Kang Man; Koo, Mi Jeong; Choi, Won Jun; Kim, Hea Ok; Moon, Hyung Ryong; Lee, Min Young; Park, Jae Gyu; Lee, Sang Kook Journal of Medicinal Chemistry (2003), 46(2), 201-203.

26. Stereoselective synthesis of a novel apio analogue of neplanocin A as potential S-adenosylhomocysteine hydrolase inhibitor Moon, Hyung Ryong; Kim, Hea Ok; Lee, Kang Man; Chun, Moon Woo; Kim, Joong Hyup; Jeong, Lak Shin Organic Letters (2002), 4(20), 3501-3503.

25. Enantioselective Synthesis of Bicyclo[3.1.0]hexane Carbocyclic Nucleosides via a Lipase-Catalyzed Asymmetric Acetylation. Characterization of an Unusual Acetal Byproduct Yoshimura, Yuichi; Moon, Hyung R.; Choi, Yongseok; Marquez, Victor E. Journal of Organic Chemistry (2002), 67(17), 5938-5945.

24. Synthesis and Biological Evaluation of Novel D-2'-Azido-2',3'-dideoxyarabinofuranosyl-4'-thiopyrimidines and purines Kim, Hea Ok; Park, Yong Hee; Moon, Hyung Ryong; Jeong, Lak Shin Bioorganic & Medicinal Chemistry Letters (2002), 12(17), 2403-2406.

23. Synthesis of 2',3'-didehydro-2',3'-dideoxy-2'-fluoro apionucleosides as potential antiviral agents Moon, Hyung Ryong; Kim, Hea Ok; Jeong, Lak Shin Journal of the Chemical Society, Perkin Transactions 1 (2002), (15), 1800-1804.

22. Improved and alternative synthesis of D- and L-cyclopentenone derivatives, the versatile intermediates for the synthesis of carbocyclic nucleosides Moon, Hyung Ryong; Choi, Won Jun; Kim, Hea Ok; Jeong, Lak Shin Tetrahedron: Asymmetry (2002), 13(11), 1189-1193.

21. Synthesis and biological evaluation of novel thioapio dideoxynucleosides Moon, Hyung Ryong; Kim, Hea Ok; Lee, Sang Kook; Choi, Won Jun; Chun, Moon Woo; Jeong, Lak Shin Bioorganic & Medicinal Chemistry (2002), 10(5), 1499-1507.

20. Synthesis of Novel D-2'-Deoxy-2'-C-difluoromethylene-4'-thiocytidine as a Potential Antitumor Agent Lim, Moo Hong; Kim, Hea Ok; Moon, Hyung Ryong; Chun, Moon Woo; Jeong, Lak Shin Organic Letters (2002), 4(4), 529-531.

19. Syntheses of D- and L-Cyclopentenone Derivatives Using Ring-Closing Metathesis: Versatile Intermediates for the Synthesis of D- and L-Carbocyclic Nucleosides Choi, Won Jun; Park, Jae Gyu; Yoo, Su Jeong; Kim, Hea Ok; Moon, Hyung Ryong; Chun, Moon Woo; Jung, Young Hoon; Jeong, Lak Shin Journal of Organic Chemistry (2001), 66(19), 6490-6494.

18. Synthesis and antiviral activity of fluoro-substituted apio dideoxynucleosides Hong, Joon Hee; Kim, Hea Ok; Moon, Hyung Ryong; Jeong, Lak Shin Archives of Pharmacal Research (2001), 24(2), 95-99.

17. Syntheses and Structure-Activity Relationships of Novel Apio and Thioapio Dideoxydidehydronucleosides as Anti-HCMV Agents Jeong, Lak Shin; Kim, Hea Ok; Moon, Hyung Ryong; Hong, Joon Hee; Yoo, Su Jeong; Choi, Won Jun; Chun, Moon Woo; Lee, Chong-Kyo Journal of Medicinal Chemistry (2001), 44(5), 806-813.

16. A highly efficient synthesis of L-β-2'-deoxy-4'-thio-1'-purine nucleosides as potential antiviral agents Kim, Hea Ok; Jeong, Lak Shin; Lee, Sun Nan; Yoo, Soo Jeong; Moon, Hyung Ryong; Kim, Kil Soo; Chun, Moon Woo Perkin 1 (2000), (9), 1327-1329.

15. A Remarkably Simple Chemi-coenzymatic Approach to Structurally Complex Bicyclo[3.1.0]hexane Carbocyclic Nucleosides Moon, Hyung R.; Ford, Harry, Jr.; Marquez, Victor E. Organic Letters (2000), 2(24), 3793-3796.

14. Construction of the Bicyclo[3.1.0]hexane Template of a Conformationally Locked Carbocyclic Adenosine via an Olefin Keto-Carbene Cycloaddition Shin, Kye Jung; Moon, Hyung Ryong; George, Clifford; Marquez, Victor E. Journal of Organic Chemistry (2000), 65(7), 2172-2178.

13. Synthesis and hybridization property of sugar and phosphate linkage modified oligonucleotides Jeong, Lak Shin; Lee, Ji Hea; Jung, Kyeong-Eun; Moon, Hyung Ryong; Kim, Kichul; Lim, Hong Bioorganic & Medicinal Chemistry (1999), 7(7), 1467-1473.

12. Synthesis and antiviral activity of D- and L-isodideoxy nucleosides with exocyclic methylene Jeong, Lak Shin; Yoo, Su Jeong; Moon, Hyung Ryong; Chun, Moon Woo; Lee, Chong-Kyo Nucleosides & Nucleotides (1999), 18(4 & 5), 655-656.

11. Synthesis and antiviral activities of 1,3-oxathiolanyl nucleosides with 5-hydroxymethyl substituent Chun, Moon Woo; Choi, Sung Pil; Kim, Myong Jung; Bae, Chol Joon; Moon, Hyung Ryong; Kim, Hee-Doo; Jeong, Lak Shin Nucleosides & Nucleotides (1999), 18(4 & 5), 615-616.

10. Synthesis and antiviral activity of L-2'-deoxy-2'-up-fluoro-4'-thionucleosides Jeong, Lak Shin; Moon, Hyung Ryong; Yoo, Su Jeong; Lee, Sun Nan; Kim, Hee-Doo; Chun, Moon Woo Nucleosides & Nucleotides (1999), 18(4 & 5), 571-572.

9. Synthesis of Cyclo propyl-Fused Carbocyclic Nucleosides via the Regioselective Opening of Cyclic Sulfites Moon, Hyung Ryong; Kim, Hea Ok; Chun, Moon Woo; Jeong, Lak Shin; Marquez, Victor E. Journal of Organic Chemistry (1999), 64(13), 4733-4741.

8. Total synthesis of (±)-iso-d4T as potential antiviral agent Jeong, Lak Shin; Lee, Young A.; Moon, Hyung Ryong; Yoo, Su Jeong; Kim, Su Youn Tetrahedron Letters (1998), 39(41), 7517-7520.

7. Participation of sulfur occurred during the Mitsunobu reaction: synthesis of novel isodideoxythionucleosides Jeong, Lak Shin; Yoo, Su Jeong; Moon, Hyung Ryong; Kim, Yun Ha; Chun, Moon Woo Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1998), (20), 3325-3326.

6. Synthesis and antiviral activity of apio dideoxy nucleosides with azido or amino substituent Jeong, Lak Shin; Lee, Young A.; Moon, Hyung Ryong; Chun, Moon Woo Nucleosides & Nucleotides (1998), 17(8), 1473-1487.

5. A Short and Efficient Synthesis of L-Thioarabinose Derivative: A Versatile Synthon for the Synthesis of L-2'-Deoxy-2',2'-disubstituted-4'-thionucleosides Jeong, Lak Shin; Moon, Hyung Ryong; Choi, Yeon Ju; Chun, Moon Woo; Kim, Hea Ok Journal of Organic Chemistry (1998), 63(14), 4821-4825.

4. Ring contraction and rearrangement of 4-thiofuranose derivatives observed during DAST fluorination in the synthesis of L-2'-"up"-fluoro-4'-thiothymidine Jeong, Lak Shin; Moon, Hyung Ryong; Yoo, Su Jeong; Lee, Sun Nan; Chun, Moon Woo; Lim, Yoong-Ho Tetrahedron Letters (1998), 39(29), 5201-5204.

3. Syntheses and antiviral activities of 1,3-dioxolanyl-, 1,3-oxathiolanyl- and 1,3-dithiolanylnucleosides with 2-hydroxymethyl substituents Chun, Moon Woo; Shin, Dae Hong; Moon, Hyung Ryong; Lee, Jeewoo; Park, Hokoon; Jeong, Lak Shin Bioorganic & Medicinal Chemistry Letters (1997), 7(11), 1475-1480.

2. Synthesis of acyclonucleosides. (6). Synthesis of 5'-modified-2',3'-secoribavirins Moon, Hyung Ryong; Ha, Eun Young; Yang, Jae Wook; Chun, Moon Woo; Chung, Won Keun Soul Taehakkyo Yakhak Nonmunjip (1990), 15, 100-5.

1. Synthesis of acyclonucleosides. (3). Synthesis of ribavirin derivatives Moon, Hyung Ryong; Yang, Jae Wook; Kim, Moon Hwan; Chun, Moon Woo; Chung, Won Keun Yakhak Hoechi (1989), 33(6), 361-4.