Biopharmaceutics is the study of the fate of drugs in biological systems after administration (i.e., absorption, distribution, metabolism, and excretion; ADME) and its mechanisms. Pharmacokinetics is the science of the kinetics of drug ADME. The study of biopharmaceutics and pharmacokinetics is based on fundamental scientific principles and techniques developed in the fields of anatomy, physiology, biology, engineering mathematics, statistics, etc. Biopharmaceutics and pharmacokinetics provide the scientific basis for design and development of drug products and dosage regimens. In particular, scientists in the fields of biopharmaceutics and pharmacokinetics can collaborate closely with those of pharmaceutics, physical pharmacy, pharmacology, toxicology, clinical pharmacy, etc., and contribute eventually to the optimization of drug delivery and therapy. In our laboratory, we are mainly working on the following research topics by using various in vitro/in vivo experimental and in silico kinetic modeling approaches.

- Metabolizing enzymes- and transporters-mediated absorption and disposition of xenobiotics
- Drug-drug/food/natural product interactions
- Quantitative determination of drugs/phytochemicals in biological fluids
- Physiologically-based pharmacokinetic modeling & simulation
- Oral/transdermal drug absorption & formulation

Selected Publications

Web Link to the Full List of Prof. In-Soo Yoon’s Research Achievements:

1. Google Scholar
   http://scholar.google.co.kr/citations?hl=ko&user=u3BSd3gAAAAJ&view_op=list_works&sortby=pubdate
2. ResearchGate
   https://www.researchgate.net/profile/In-Soo_Yoon